Genomic analysis of pilocytic astrocytomas at 0.97 Mb resolution shows an increasing tendency toward chromosomal copy number change with age.
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Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypesMAPK pathway activation in pilocytic astrocytomaThe molecular biology of WHO grade I astrocytomasTandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomasGenome-wide analysis of subependymomas shows underlying chromosomal copy number changes involving chromosomes 6, 7, 8 and 14 in a proportion of cases.Pediatric low-grade gliomas and the need for new options for therapy: Why and how?Pediatric low-grade gliomas.Biology, genetics and imaging of glial cell tumoursPrognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trialBRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas.Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age.Genomic deletions correlate with underexpression of novel candidate genes at six loci in pediatric pilocytic astrocytomaTreatment of pediatric brain tumors.Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status.Epigenetic markers in human gliomas: prospects for therapeutic intervention.Pediatric brain tumors: current treatment strategies and future therapeutic approachesTreatment of posterior fossa tumors in children.Long-term epilepsy-associated tumors.Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma.The potential for epigenetic analysis of paediatric CNS tumours to improve diagnosis, treatment and prognosis.Pilocytic astrocytoma: pathology, molecular mechanisms and markers.Genetic changes observed in a case of adult pilocytic astrocytoma revealed by array CGH analysisCRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles.Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain.Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytRAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology.Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytomaIDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomasOncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma.Molecular Basis of Pediatric Brain Tumors.Biologic tumor behavior in pilocytic astrocytomas.MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations.Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization.Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence.
P2860
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P2860
Genomic analysis of pilocytic astrocytomas at 0.97 Mb resolution shows an increasing tendency toward chromosomal copy number change with age.
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2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
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name
Genomic analysis of pilocytic ...... l copy number change with age.
@en
Genomic analysis of pilocytic ...... l copy number change with age.
@nl
type
label
Genomic analysis of pilocytic ...... l copy number change with age.
@en
Genomic analysis of pilocytic ...... l copy number change with age.
@nl
prefLabel
Genomic analysis of pilocytic ...... l copy number change with age.
@en
Genomic analysis of pilocytic ...... l copy number change with age.
@nl
P2093
P2860
P1476
Genomic analysis of pilocytic ...... al copy number change with age
@en
P2093
Danita M Pearson
Karen Plant
Koichi Ichimura
V Peter Collins
P2860
P304
P356
10.1097/01.JNEN.0000240465.33628.87
P577
2006-11-01T00:00:00Z