Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
about
Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signallingRaf family kinases: old dogs have learned new tricksToward a Molecular Classification of Colorectal Cancer: The Role of BRAFTo BRAF or not to BRAF: is that even a question anymore?Modern brain tumor imagingMAPK pathway activation in pilocytic astrocytomaThe molecular biology of WHO grade I astrocytomasWill kinase inhibitors make it as glioblastoma drugs?Pathological and molecular advances in pediatric low-grade astrocytomaTargeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondGenetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in miceRaf kinases in cancer-roles and therapeutic opportunitiesPilocytic astrocytoma: a disease with evolving molecular heterogeneityExome sequencing identifies BRAF mutations in papillary craniopharyngiomasBRAF V600E-mutated diffuse glioma in an adult patient: a case report and review.A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Gliomas in adults.Pediatric low-grade gliomas: how modern biology reshapes the clinical field.BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Activation of the Hedgehog pathway in pilocytic astrocytomas.PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumorsPhase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.Biology, genetics and imaging of glial cell tumoursRecurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.The landscape of kinase fusions in cancerA multivariate analysis of factors determining tumor progression in childhood low-grade glioma: a population-based cohort study (CCLG CNS9702)MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in miceChromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.The BRAF kinase domain promotes the development of gliomas in vivo.Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells.Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma.KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.A pilot study using carboplatin, vincristine, and temozolomide in children with progressive/symptomatic low-grade glioma: a Children's Oncology Group study†Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma.Emerging insights into the molecular and cellular basis of glioblastoma.
P2860
Q24314807-CF245782-7404-4515-A571-D81FDFF84570Q24316181-54218F20-3F83-46B8-A830-E86CAC0D5F33Q26827212-402070AC-9C0B-4839-B5BA-9F98CD7B4C9FQ26829788-49EA7CE6-3B15-4609-B7A2-3C60E7FC68EBQ27002344-5E578CF3-A840-4774-9411-3EEDC26CBAD8Q27006028-3C699C1B-6496-4CA1-8A5C-B4FE34C8730BQ27010414-E72BA266-4FF0-4A15-A15C-94D2E767D077Q27012684-4B7DB593-4B1C-4489-8D31-33DEF72350C0Q27026123-7000CA59-87F7-42F9-B273-89BF3C4B99E3Q27026323-0ECC1D8B-16AF-4C87-AF30-102902972068Q27332453-DAFB2FDD-15AA-4D9E-81B2-68288D14172AQ28237793-983811CD-91F3-4946-A7D7-55E23E83D4F2Q28286218-F9F9D803-1E5B-4F98-84B1-0C9B856BEC77Q28305680-54C28ABE-E9C1-4B1E-8F5B-64B229C5C172Q31002780-F68F8669-1150-4EB8-A98F-D2D6E59A2A2BQ33610906-218689FA-66AC-48EB-9F4C-0C098E8C1FF1Q33760539-6B30C7D7-7345-41E3-AED0-9304AE1F7C91Q33847771-D9B53782-3BA6-4926-BC0C-B81B3A52CA58Q33867475-A913E736-284F-45B5-B0FE-280F652322B7Q33945989-63B0CBBF-648A-4DE2-8C24-EC460C17C773Q34133052-80E99908-3749-4EFE-8B1D-8A136701108CQ34164924-646AC998-03DB-48B7-9637-3A60DB4650C2Q34166553-1122D197-363C-4C1F-B829-722F1DC51624Q34183147-A5F38820-0619-4B9E-A448-469518722024Q34203979-1BF58AFA-F0ED-4A41-A1B3-AE13F67341F9Q34354839-9491D28A-DBBD-4D95-A44A-829C35FB8F1DQ34415484-E465C4FA-66A5-4396-A588-DCEFBD2B0BC8Q34437602-CDED81E4-9D95-44E4-B166-C08CE1A58C0AQ34480657-6740D792-27ED-4027-BEB2-57FBCF7EC0A9Q34734398-1279E463-9720-4DAF-BDA0-CFE59DA4DB40Q34755317-E76EFCF6-A85E-4CAD-933A-2F499F9E6256Q34810518-554FF621-0940-4B76-9DF7-8B977B19E1EFQ35184491-E78C07E8-88D4-4CC9-B03D-A5DDD7A48994Q35238436-D36A1A64-EDA6-4621-B246-11E1A15E6C5EQ35348996-4970CEEA-4705-4B55-8213-B4183925276AQ35751428-1A59DD63-E787-479E-AFD2-508A4CF5210FQ35754390-7CAC2417-22E7-405E-ADF9-994AAF4286A6Q35815306-EB9B0ADD-90F1-4DE9-895F-05BB1FF5F34BQ35882807-84ED3F5B-8161-434F-B652-F37A39A20BB7Q35914897-5434FFB3-43A8-4AF1-AA62-6DA65030E0CA
P2860
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Oncogenic RAF1 rearrangement a ...... thway in pilocytic astrocytoma
@en
type
label
Oncogenic RAF1 rearrangement a ...... thway in pilocytic astrocytoma
@en
prefLabel
Oncogenic RAF1 rearrangement a ...... thway in pilocytic astrocytoma
@en
P2093
P2860
P356
P1433
P1476
Oncogenic RAF1 rearrangement a ...... thway in pilocytic astrocytoma
@en
P2093
D M Pearson
D T W Jones
K Ichimura
S Kocialkowski
V P Collins
P2860
P2888
P304
P356
10.1038/ONC.2009.73
P407
P577
2009-04-13T00:00:00Z
P5875
P6179
1044760679