Retinoblastoma family protein promotes normal R8-photoreceptor differentiation in the absence of rhinoceros by inhibiting dE2F1 activity.
about
The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila developmentTargeting Rb inactivation in cancers by synthetic lethality.Role of Drosophila retinoblastoma protein instability element in cell growth and proliferationHyperactivated Wnt signaling induces synthetic lethal interaction with Rb inactivation by elevating TORC1 activities.RBF and Rno promote photoreceptor differentiation onset through modulating EGFR signaling in the Drosophila developing eyeRb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells.ESCRT-0 complex modulates Rbf-mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signalingConserved RB functions in development and tumor suppression.Specific killing of Rb mutant cancer cells by inactivating TSC2.Deregulated G1-S control and energy stress contribute to the synthetic-lethal interactions between inactivation of RB and TSC1 or TSC2.
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P2860
Retinoblastoma family protein promotes normal R8-photoreceptor differentiation in the absence of rhinoceros by inhibiting dE2F1 activity.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
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Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
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type
label
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
@en
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
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prefLabel
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
@en
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
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P2093
P2860
P1476
Retinoblastoma family protein ...... by inhibiting dE2F1 activity.
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Gabriel M Gordon
Latishya Steele
Madina J Sukhanova
Yongsheng Huang
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P304
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10.1016/J.YDBIO.2009.09.004
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P577
2009-09-08T00:00:00Z