Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs.
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Central role of the P2Y12 receptor in platelet activationS-nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.Platelet signalingP2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteriesImpaired activation of murine platelets lacking G alpha(i2)ADP and platelets: the end of the beginningActivation of Gz attenuates Rap1-mediated differentiation of PC12 cellsA role for G(z) in pancreatic islet beta-cell biologyGpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviourPlatelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy.Glycerophospholipid molecular species in platelets and brain tissues - are platelets a good model for neurons?Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout.Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.Gαz regulates BDNF-induction of axon growth in cortical neurons.Analysis of candidate genes for morphine preference quantitative trait locus Mop2G(z) signaling: emerging divergence from G(i) signaling.In vivo functions of heterotrimeric G-proteins: studies in Galpha-deficient mice.Understanding the role of prostaglandin E2 in regulating human platelet activity in health and diseaseSignaling during platelet adhesion and activationGas1 is a receptor for sonic hedgehog to repel enteric axons.Activation of heterotrimeric G proteins by Smoothened.Protease-activated receptors in the cardiovascular system.Contact-dependent signaling during the late events of platelet activation.Inherited defects in platelet signaling mechanisms.A critical role for the transient receptor potential channel type 6 in human platelet activationDeletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell massPlatelets in atherothrombosis: lessons from mouse models.A guide to murine platelet structure, function, assays, and genetic alterations.CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets.Platelet receptors and signaling in the dynamics of thrombus formation.The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.Platelet receptor signaling in thrombus formation.Regulating thrombus growth and stability to achieve an optimal response to injury.P2Y12 receptor: platelet thrombus formation and medical interventions.Harnessing the platelet signaling network to produce an optimal hemostatic response.The P2X1 receptor and platelet function.Galphaz negatively regulates insulin secretion and glucose clearance.Phosphorylation-regulated inhibition of the Gz GTPase-activating protein activity of RGS proteins by synapsin I.
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P2860
Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2000
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Loss of signaling through the ...... sponses to psychoactive drugs.
@en
Loss of signaling through the ...... sponses to psychoactive drugs.
@nl
type
label
Loss of signaling through the ...... sponses to psychoactive drugs.
@en
Loss of signaling through the ...... sponses to psychoactive drugs.
@nl
prefLabel
Loss of signaling through the ...... sponses to psychoactive drugs.
@en
Loss of signaling through the ...... sponses to psychoactive drugs.
@nl
P2093
P2860
P356
P1476
Loss of signaling through the ...... sponses to psychoactive drugs.
@en
P2093
J A Blendy
P J O'Brien
P2860
P304
P356
10.1073/PNAS.180194597
P407
P577
2000-08-01T00:00:00Z