Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells.
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Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesisDifferential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductaseHypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cellsHigh resolution ultra high field magnetic resonance imaging of glioma microvascularity and hypoxia using ultra-small particles of iron oxideRegulation of E-cadherin: does hypoxia initiate the metastatic cascade?Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.Imaging hypoxia in gliomas.Identification of methotrexate transport deficiency in mammalian cells using fluoresceinated methotrexate and flow cytometryFrequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistanceTumor hypoxia and genetic alterations in sporadic cancers.Radiation sensitivity of tumour cells stained in vitro or in vivo with the bisbenzimide fluorochrome Hoechst 33342.Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistanceEnvironmental stress induces trinucleotide repeat mutagenesis in human cells.The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosisCancer Exosomes as Mediators of Drug Resistance.Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxiaBioreductive drugs and the selective induction of tumour hypoxia.Enhanced synthesis of stress proteins caused by hypoxia and relation to altered cell growth and metabolism.Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells.Chromosomal instability in oral cancer cells.Correlation of P-glycoprotein expression with poor vascularization in human gallbladder carcinomas.Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma.In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo.Regulation of c-jun expression during hypoxic and low-glucose stress.Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.Evolution and stability of chromosomal DNA coamplified with the CAD geneEffect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis.Herpes simplex virus virion host shutoff functionRedox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesInhibition of apoptosis by overexpressing Bcl-2 enhances gene amplification by a mechanism independent of aphidicolin pretreatment.The tumor microenvironment and DNA repair.1,3-Butadiene: II. Genotoxicity profile.Tumor hypoxia as a driving force in genetic instability.Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironmentComplex effects of tumor microenvironment on the tumor disposition of carrier-mediated agents.Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.Hypoxia-induced tetraploidisation of a diploid human melanoma cell line in vitro.Chromosome number variation in three mouse embryonic stem cell lines during culture.Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage.
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P2860
Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1986
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@en
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@nl
type
label
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@en
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@nl
prefLabel
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@en
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@nl
P2093
P2860
P356
P1476
Transient hypoxia enhances the ...... n Chinese hamster ovary cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.16.5978
P407
P577
1986-08-01T00:00:00Z