Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.
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Inferring clonal composition from multiple sections of a breast cancerEvaluation and consequences of heterogeneity in the circulating tumor cell compartmentTumour Cell HeterogeneitySomatic mutations in breast and serous ovarian cancer young patients: a systematic review and meta-analysisRethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancerThe path to routine use of genomic biomarkers in the cancer clinicMaintaining Tumor Heterogeneity in Patient-Derived Tumor XenograftsHarnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian CancerTranslational implications of tumor heterogeneityDeciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicineTumour heterogeneity and the evolution of polyclonal drug resistanceBetter therapeutic trials in ovarian cancer.Personalized oncogenomics: clinical experience with malignant peritoneal mesothelioma using whole genome sequencing.Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and TreatmentPatient-derived tumour xenografts for breast cancer drug discoveryChanging genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationshipsSpatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysisRationale for Developing a Specimen Bank to Study the Pathogenesis of High-Grade Serous Carcinoma: A Review of the EvidenceTITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data.Using high-sensitivity sequencing for the detection of mutations in BTK and PLCγ2 genes in cellular and cell-free DNA and correlation with progression in patients treated with BTK inhibitorseTumorType, An Algorithm of Discriminating Cancer Types for Circulating Tumor Cells or Cell-free DNAs in Blood.Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrationsGenetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine.The NF1 somatic mutational landscape in sporadic human cancers.Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma.Identification of two poorly prognosed ovarian carcinoma subtypes associated with CHEK2 germ-line mutation and non-CHEK2 somatic mutation gene signatures.Tumor heterogeneity in the recurrence of epithelial ovarian cancer demonstrated by polycomb group proteinsPyClone: statistical inference of clonal population structure in cancer.Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancerAssessing intratumor heterogeneity and tracking longitudinal and spatial clonal evolutionary history by next-generation sequencing.Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancerIntratumoral heterogeneity in a minority of ovarian low-grade serous carcinomasTumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencingExpression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease.Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer.Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.Fast and scalable inference of multi-sample cancer lineagesIntra-tumor heterogeneity in TP53 null High Grade Serous Ovarian Carcinoma progressionSingle-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells.
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Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Distinct evolutionary trajecto ...... spatial mutational profiling.
@en
Distinct evolutionary trajecto ...... spatial mutational profiling.
@nl
type
label
Distinct evolutionary trajecto ...... spatial mutational profiling.
@en
Distinct evolutionary trajecto ...... spatial mutational profiling.
@nl
prefLabel
Distinct evolutionary trajecto ...... spatial mutational profiling.
@en
Distinct evolutionary trajecto ...... spatial mutational profiling.
@nl
P2093
P2860
P356
P1476
Distinct evolutionary trajecto ...... spatial mutational profiling.
@en
P2093
Ali Bashashati
Alicia Tone
Andrew Roth
Blake Gilks
David G Huntsman
Jamie Rosner
Janine Senz
Jessica N McAlpine
Jiarui Ding
P2860
P356
10.1002/PATH.4230
P577
2013-09-01T00:00:00Z