Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination.
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A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphomaStructural basis for G.C recognition in the DNA minor grooveRecognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligandsNext generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Drug-DNA recognition: energetics and implications for design.Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes.Optimization of alternate-strand triple helix formation at the 5"-TpA-3" and 5"-ApT-3" junctions.DNA sequence selectivity of hairpin polyamide turn unitsDesign of sequence-specific DNA binding molecules for DNA methyltransferase inhibition.Sequence-based design of bioactive small molecules that target precursor microRNAs.Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.A Bis(guanidinium)alcohol Attached to a Hairpin Polyamide: Synthesis, DNA Binding, and Plasmid Cleavage.Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAsCyclic pyrrole-imidazole polyamides targeted to the androgen response element.Energetic basis for selective recognition of T*G mismatched base pairs in DNA by imidazole-rich polyamides.The hybridization-stabilization assay: a solution-based isothermal method for rapid screening and determination of sequence preference of ligands that bind to duplexed nucleic acidsBinding of bis-linked netropsin derivatives in the parallel-stranded hairpin form to DNA.DNA sequence recognition by an isopropyl substituted thiazole polyamide.Hairpin polyamides that use parallel and antiparallel side-by-side peptide motifs in binding to DNA.Sequence-specific recognition of DNA by hydrophobic, alanine-rich mutants of the basic region/leucine zipper motif investigated by fluorescence anisotropy.Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides.DNA methylation reduces binding and cleavage by bleomycin.Quantitation of pyrrole-imidazole polyamide in rat plasma by high-performance liquid chromatography coupled with UV detection.Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.Structural and energetic insights into sequence-specific interaction in DNA-drug recognition: development of affinity predictor and analysis of binding selectivity.A polyamide inhibits replication of vesicular stomatitis virus by targeting RNA in the nucleocapsid.Teaching an old scaffold new recognition tricks: oligopyrrolamide antagonists of IAPP aggregation.Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.
P2860
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P2860
Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@en
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@nl
type
label
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@en
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@nl
prefLabel
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@en
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@nl
P2093
P2860
P356
P1476
Binding of a hairpin polyamide ...... ific enthalpic discrimination.
@en
P2093
C A Gelfand
K J Breslauer
P B Dervan
P2860
P304
P356
10.1073/PNAS.93.16.8306
P407
P577
1996-08-01T00:00:00Z