Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
about
Antitumor activity of a pyrrole-imidazole polyamideStructural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor BindingSequence-specific positions of water molecules at the interface between DNA and minor groove binders.Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.Binding studies of a large antiviral polyamide to a natural HPV sequence.Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.Synthesis of cyclic Py-Im polyamide libraries.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.DNA sequence selectivity of hairpin polyamide turn unitsEnhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear.Microwave assisted synthesis of Py-Im polyamides.Characterization and solubilization of pyrrole-imidazole polyamide aggregatesSingle-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice.Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.Solution-phase synthesis of pyrrole-imidazole polyamidesAnimal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit.Oligomerization route to Py-Im polyamide macrocycles.RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motifAddressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides.G-quadruplex nucleic acids as therapeutic targets.Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine.Synergetic DNA-cleaving activities of the metal complexes of a polyether-tethered pyrrole-polyamide dimer.
P2860
Q24628320-38011309-17A0-4A46-B00B-5D9322B3D9BFQ27664249-55411468-C87D-4539-B4AD-6C976DCEFEDFQ33386322-A86CEA94-BE44-4E70-BF81-92EB0829F826Q33477522-4E02277F-4402-46B1-A9EA-392057F5ED1BQ33717554-B9FCDCE1-9F4E-4B44-9B2B-7190FF2EC2C1Q34421960-33F3D4B0-D760-4BEE-8305-4000CF7115E1Q34459196-998D2473-3D75-42D1-A317-5915556B483BQ34697484-05CAD8BC-529B-4A57-8ACC-A0D3272DF852Q34708077-CC74A8BA-1986-4425-95A5-8B9241C905E3Q35823735-F8DE3BDB-B4B4-468E-BA25-3F72355688F5Q35842218-30A84A48-9B94-46CC-A5E8-86725DD7A39AQ35949095-486604EE-362C-4DFC-B540-676866CDD6CFQ36002250-52ED6FA3-2FD5-4A1D-AB65-7DFB703B006DQ36031605-2B78DC20-7348-4D7F-8018-5B9044A31D71Q36275422-BF499BB5-C349-4D05-B614-35A7A98125DAQ36749396-2DFF952D-5D38-4F91-BCBA-4E6EFFC3F344Q37209293-CD3D2937-022C-47BB-BBDB-42A16191EF8BQ37209301-1D1D39FA-86EC-4C70-A9D5-5BC19FB3953CQ37210876-0F42DBB5-0F0A-4EFA-BD39-BBAC363BCDFEQ37329318-1DF3403C-09EC-497B-90C3-AC0B03FA6D5EQ37398257-1DA794F7-92D5-4B81-9D3F-84D7533649AFQ40994868-C01DD1DA-E8B3-4854-92DA-8AE203540D6BQ41786267-7459ED56-53E9-459E-B218-CF6875DDA2ADQ43055394-E93E0C4C-7239-4A98-8EC9-A775E8D89012Q43714026-D4574249-9C61-4688-AC30-F2CD5161876C
P2860
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@ast
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@en
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@nl
type
label
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@ast
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@en
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@nl
prefLabel
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@ast
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@en
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@nl
P2860
P50
P356
P1476
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
@en
P2093
Michelle E Farkas
P2860
P304
P356
10.1021/JA800888D
P407
P577
2008-05-07T00:00:00Z