Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding. - Wikidata - wikimedia - TriplyDB

Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding.

Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding.

http://www.wikidata.org/entity/Q37402802

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A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel Opposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.Structural Models of Ligand-Bound Sodium Channels.Effect of dibucaine hydrochloride on raft-like lipid domains in model membrane systems

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Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding.

http://www.wikidata.org/entity/Q37402802

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Novel molecular determinants i ...... late local anesthetic binding.

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Novel molecular determinants i ...... late local anesthetic binding.

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type

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Novel molecular determinants i ...... late local anesthetic binding.

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Novel molecular determinants i ...... late local anesthetic binding.

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Novel molecular determinants i ...... late local anesthetic binding.

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Novel molecular determinants i ...... late local anesthetic binding.

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Molecular Pharmacology

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Novel molecular determinants i ...... late local anesthetic binding.

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Ailsa Méndez-Fitzwilliam

http://www.w3.org/2001/XMLSchema#string

Andre Kondratiev

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Eduardo Marbán

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Gordon F Tomaselli

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Jeffrey R Balser

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Patricio Vélez

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Toshio Yamagishi

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Wei Xiong

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P2860

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibule

Structure of the sodium channel pore revealed by serial cysteine mutagenesis.

Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel.

Sodium channel selectivity filter regulates antiarrhythmic drug binding

Topology of the P segments in the sodium channel pore revealed by cysteine mutagenesis

Molecular motions within the pore of voltage-dependent sodium channels

Fast lidocaine block of cardiac and skeletal muscle sodium channels: one site with two routes of access.

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861-871

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scholarly article

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10.1124/MOL.109.055863

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4

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76

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2009-07-20T00:00:00Z

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26683942

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19620257

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2769053

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