Reconstruction of functionally normal and malignant human breast tissues in mice
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Interaction of tumor cells with the microenvironmentCancer as an evolutionary and ecological processRadiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor typeEndocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenograftsOCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast CancerTumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomesAldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesisMatrix crosslinking forces tumor progression by enhancing integrin signalingA collection of breast cancer cell lines for the study of functionally distinct cancer subtypesAldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancerALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcomeNew highlights on stroma-epithelial interactions in breast cancer.Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts.Ovarian cancer, the coagulation pathway, and inflammationFibroblasts, an inconspicuous but essential player in colon cancer development and progressionHZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary CarcinogenesisCapturing relevant extracellular matrices for investigating cell migrationBreast Cancer-Associated Fibroblasts: Where We Are and Where We Need to GoThe Role of Stroma in Tumor DevelopmentTumors: wounds that do not heal-reduxRebuilding cancer metastasis in the mousec-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic CascadeOne mouse, one patient paradigm: New avatars of personalized cancer therapyPatient-derived xenograft models of breast cancer and their predictive powerA synthetic modular approach for modeling the role of the 3D microenvironment in tumor progressionUnderstanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer modelsTransient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancerIn vitro models of cancer stem cells and clinical applicationsBiology of MET: a double life between normal tissue repair and tumor progressionHedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cellsGenome remodelling in a basal-like breast cancer metastasis and xenograftTumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancerA FTIR imaging characterization of fibroblasts stimulated by various breast cancer cell linesTGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling MechanismsBreast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesisMultiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markersRepurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiationTumour heterogeneity and cancer cell plasticityStromal fibroblasts in cancer initiation and progressionPathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ
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P2860
Reconstruction of functionally normal and malignant human breast tissues in mice
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 March 2004
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Reconstruction of functionally normal and malignant human breast tissues in mice
@en
Reconstruction of functionally normal and malignant human breast tissues in mice.
@nl
type
label
Reconstruction of functionally normal and malignant human breast tissues in mice
@en
Reconstruction of functionally normal and malignant human breast tissues in mice.
@nl
prefLabel
Reconstruction of functionally normal and malignant human breast tissues in mice
@en
Reconstruction of functionally normal and malignant human breast tissues in mice.
@nl
P2093
P2860
P356
P1476
Reconstruction of functionally normal and malignant human breast tissues in mice
@en
P2093
Andrea Richardson
Charlotte Kuperwasser
Greg Magrane
Joe W Gray
Loucinda Carey
Tony Chavarria
P2860
P304
P356
10.1073/PNAS.0401064101
P407
P577
2004-03-29T00:00:00Z