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Reconstruction of functionally normal and malignant human breast tissues in mice

Reconstruction of functionally normal and malignant human breast tissues in mice

http://www.wikidata.org/entity/Q37415657

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Interaction of tumor cells with the microenvironment Cancer as an evolutionary and ecological process Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis Matrix crosslinking forces tumor progression by enhancing integrin signaling A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome New highlights on stroma-epithelial interactions in breast cancer.Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts.Ovarian cancer, the coagulation pathway, and inflammation Fibroblasts, an inconspicuous but essential player in colon cancer development and progression HZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary Carcinogenesis Capturing relevant extracellular matrices for investigating cell migration Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go The Role of Stroma in Tumor Development Tumors: wounds that do not heal-redux Rebuilding cancer metastasis in the mouse c-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic Cascade One mouse, one patient paradigm: New avatars of personalized cancer therapy Patient-derived xenograft models of breast cancer and their predictive power A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer In vitro models of cancer stem cells and clinical applications Biology of MET: a double life between normal tissue repair and tumor progression Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells Genome remodelling in a basal-like breast cancer metastasis and xenograft Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer A FTIR imaging characterization of fibroblasts stimulated by various breast cancer cell lines TGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling Mechanisms Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation Tumour heterogeneity and cancer cell plasticity Stromal fibroblasts in cancer initiation and progression Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ

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P2860

Reconstruction of functionally normal and malignant human breast tissues in mice

http://www.wikidata.org/entity/Q37415657

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 29 March 2004

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Reconstruction of functionally normal and malignant human breast tissues in mice

@en

Reconstruction of functionally normal and malignant human breast tissues in mice.

@nl

type

label

Reconstruction of functionally normal and malignant human breast tissues in mice

@en

Reconstruction of functionally normal and malignant human breast tissues in mice.

@nl

prefLabel

Reconstruction of functionally normal and malignant human breast tissues in mice

@en

Reconstruction of functionally normal and malignant human breast tissues in mice.

@nl

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PNAS.0401064101

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Reconstruction of functionally normal and malignant human breast tissues in mice

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Andrea Richardson

http://www.w3.org/2001/XMLSchema#string

Charlotte Kuperwasser

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Greg Magrane

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Joe W Gray

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Loucinda Carey

http://www.w3.org/2001/XMLSchema#string

Min Wu

http://www.w3.org/2001/XMLSchema#string

Tony Chavarria

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P2860

The microenvironment of the tumour-host interface

High-speed analysis of multiplexed short tandem repeats with an electrophoretic microdevice.

Reconstituted normal human breast in nude mice: effect of host pregnancy environment and human chorionic gonadotropin on proliferation.

The potential influence of radiation-induced microenvironments in neoplastic progression.

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane.

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation

Estrogen receptor-positive proliferating cells in the normal and precancerous breast.

Frequency of benign and malignant breast lesions in 207 consecutive autopsies in Australian women

Breast cancer and atypia among young and middle-aged women: a study of 110 medicolegal autopsies

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4966-4971

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scholarly article

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10.1073/PNAS.0401064101

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101

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Robert Weinberg

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2004-03-29T00:00:00Z

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8649051

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15051869

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387357

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