Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond.
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Update in asthma 2009Emerging therapies for severe asthmaRegulation of Adaptive Immunity in Health and Disease by Cholesterol MetabolismSelf-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammationDual oxidase regulates neutrophil recruitment in allergic airwaysStatins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell diseaseSimvastatin attenuates rhinovirus-induced interferon and CXCL10 secretion from monocytic cells in vitroBody mass index is a stronger predictor than the metabolic syndrome for future asthma in women. The longitudinal CARDIA study.Controversial data on simvastatin in asthma: What about the rat model?Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial.Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae.Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosisAttenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?Novel therapeutic strategies for adult obese asthmatics.PPARγ agonist rosiglitazone prevents perinatal nicotine exposure-induced asthma in rat offspringSimvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblastsNew and developing non-adrenoreceptor small molecule drugs for the treatment of asthma.Emerging roles for cholesterol and lipoproteins in lung disease.Statin use and asthma control in patients with severe asthma.Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanismMethacoline Challenge test as an Evaluator of Response to Statins in Bronchial Hyperresponsiveness.Is serum cholesterol a risk factor for asthma?Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use.A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors.Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.Emerging interface between metabolic syndrome and asthma.A systematic review of statin efficacy in asthma.Newer glucocorticosteroids and corticosteroid resistance reversal in asthma.Lipid-lowering drug therapies and chronic obstructive pulmonary disease: lung failure or just heart failure?Novel approaches to the management of noneosinophilic asthma.Could simvastatin be considered as a potential therapy for chronic lung diseases? A debate on the pros and cons.Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy.Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma.Perioperative protective effects of statins.Atorvastatin has a protective effect in a mouse model of bronchial asthma through regulating tissue transglutaminase and triggering receptor expressed on myeloid cells-1 expression.Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?Evaluation of atorvastatin for the treatment of patients with asthma: a double-blind randomized clinical trial.Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells.Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung-targeted approach to deliver statins.Statins and asthma: where we stand, and the next critical steps in research.
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Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 July 2009
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@en
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@nl
type
label
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@en
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
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prefLabel
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@en
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@nl
P2093
P2860
P1476
Simvastatin inhibits airway hy ...... mevalonate pathway and beyond.
@en
P2093
Amir A Zeki
Jerold Last
Lisa Franzi
Nicholas J Kenyon
P2860
P304
P356
10.1164/RCCM.200901-0018OC
P407
P577
2009-07-16T00:00:00Z