CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
about
MyD88 deficiency ameliorates β-amyloidosis in an animal model of Alzheimer's diseaseApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse modelsMechanisms of Aβ Clearance and Degradation by Glial CellsAlzheimer's Disease: Mechanism and Approach to Cell TherapyGenetics ignite focus on microglial inflammation in Alzheimer's diseaseTREM2 in CNS homeostasis and neurodegenerative diseaseMicroglial cell dysregulation in brain aging and neurodegenerationApolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's diseaseThe role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?How do immune cells support and shape the brain in health, disease, and aging?Age-dependent dysregulation of innate immunityOsmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathwayChronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) miceContemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathwaysNeuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Immunotherapeutic approaches for Alzheimer's diseaseAmyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's diseaseMechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cellsMechanisms underlying inflammation in neurodegenerationA rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.Phagocytic activity of neuronal progenitors regulates adult neurogenesis.Phagocytic clearance in neurodegeneration.Microglia demonstrate age-dependent interaction with amyloid-β fibrilsTemporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.The expression of fibronectin is significantly suppressed in macrophages to exert a protective effect against Staphylococcus aureus infectionNeurotoxic reactive astrocytes are induced by activated microglia.Inflammation, microglia, and Alzheimer's disease.Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microgliaToll-like receptor 9 is required for opioid-induced microglia apoptosis.Microglia activation and anti-inflammatory regulation in Alzheimer's diseaseHerpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2.Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional rolesHippocampal proliferation is increased in presymptomatic Parkinson's disease and due to microglia.Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosisOpposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathwayPhagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes.CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Amyloid-β(1-42) protofibrils stimulate a quantum of secreted IL-1β despite significant intracellular IL-1β accumulation in microglia.Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
P2860
Q24616286-586CC18C-8A95-41CA-9C3A-EB96E832BB7AQ24628845-3A90498D-85FF-4465-AF16-ED5F2D6F0D8AQ26741609-E41031A8-200B-4ABF-9775-EE126E6BB638Q26778149-14E36C2F-7973-4C0C-8D1D-1FC7DF76498AQ26781865-B750F8A5-AAA4-4DB2-95F1-FFE1AA94F4B1Q26785919-CB1C665C-AD46-410B-93CC-47FE9AE2E172Q26800212-0971F906-9961-4A60-82D7-8A09FCE6C9E4Q26822534-B86AC7C3-5EF4-4C9B-861C-3C689CCFF78AQ26861263-98262A70-F074-42D0-BDF5-2DB703EC6C23Q26995364-4B35694F-A921-4D79-8334-38A169968F2BQ27022410-BA7EEFF3-A5E9-48DB-953F-F99B207620ACQ27321537-EA1F92CC-10D8-44BA-8CFA-F39BA6360C3EQ27339727-17C7B348-69C7-4788-A3A0-27AE894EBDDDQ28068037-9B8720C4-D843-490B-B264-FD292E369A0DQ28070156-60896751-5AAE-44FF-9FCD-9ECC85077EA7Q28081278-1ED64A21-E0DD-4F3D-9319-63F8AB99E324Q28384947-9167C891-3489-4465-A43B-F8EAD925B934Q28392580-39DAD3D7-74B1-41F2-972B-DFCD419E68DFQ29617977-EA6A6D6B-CCE9-433B-B547-4047FCB6F793Q30273849-E8B96D52-71FB-49DB-9319-C41A440503F4Q30426473-784E97EE-11D9-40E0-B42B-6C78EBA62F3CQ30427542-28ADC974-9F77-4E84-80AF-0918CE4CAAE0Q30427927-AADBB37D-A189-4359-9269-ECB083D651C6Q33359453-278AEBF9-BCEA-483A-A870-362893BB96A8Q33560241-D5A36547-BB34-41C0-9E22-4658A0B48546Q33602850-1CD94E96-FAC9-4277-9A2A-589BD8DD0FDDQ33664099-AA14FA49-9A01-4842-AAA9-3A4EBFD3B362Q33745149-143D3DDD-A787-4141-8A5E-9A5B148A4027Q33874305-018E80AD-2AE1-4F37-94BD-0519F128207EQ33895294-32EA50F1-1BBB-48FF-9FD3-0AA8128B7D1EQ33943873-D0F733DC-782C-4599-B88B-054AEEB1EC06Q33995740-7053B503-F8F5-47C5-B1DF-8B6BD42D34E8Q34002086-4227C08E-7916-4140-8DDC-F2B775C5D5E6Q34100703-153206C0-277C-4252-87D0-0C43CDDB7CA5Q34158930-3914385A-F56C-4CF8-BEE8-00A5448DC4DCQ34162803-E60D08B7-96A1-4C52-B900-33F9D0CD82FBQ34220873-C6DC9EDD-E765-42A0-852B-84391C98245BQ34254575-1728D645-E06E-4A3F-A739-A74E410C15EBQ34302262-0646F4AE-280F-478F-8F40-B6C4DCD1234CQ34306241-D180752E-444E-471F-9418-DDFA57CE3FEC
P2860
CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@en
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@nl
type
label
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@en
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@nl
prefLabel
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@en
CD14 and toll-like receptors 2 ...... mulated microglial activation.
@nl
P2093
P2860
P1476
CD14 and toll-like receptors 2 ...... imulated microglial activation
@en
P2093
Erin G Reed-Geaghan
Gary E Landreth
Julie C Savage
P2860
P304
11982-11992
P356
10.1523/JNEUROSCI.3158-09.2009
P407
P50
P577
2009-09-01T00:00:00Z