Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma. - Wikidata - wikimedia - TriplyDB

Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma.

Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma.

http://www.wikidata.org/entity/Q37425078

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Treatment options and outcomes for glioblastoma in the elderly patient The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression Controversies in the adjuvant therapy of high-grade gliomas.MGMT promoter methylation correlates with an overall survival benefit in Chinese high-grade glioblastoma patients treated with radiotherapy and alkylating agent-based chemotherapy: a single-institution study.Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region.Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).Management of elderly patients with gliomas Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis.Concise review: bullseye: targeting cancer stem cells to improve the treatment of gliomas by repurposing disulfiram.Predictive value of MGMT promoter methylation status in Asian and Caucasian patients with malignant gliomas: a meta-analysis MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study.The prognostic value of MGMT promoter methylation in glioblastoma: A meta-analysis of clinical trials.High-mobility group box 2 is associated with prognosis of glioblastoma by promoting cell viability, invasion, and chemotherapeutic resistance Outcomes in newly diagnosed elderly glioblastoma patients after concomitant temozolomide administration and hypofractionated radiotherapy.Prognostic and predictive value of epigenetic silencing of MGMT in patients with high grade gliomas: a systematic review and meta-analysis.Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?MGMT testing--the challenges for biomarker-based glioma treatment.Treating glioblastoma in the elderly.Relationship between cognitive function and prognosis in glioblastoma.Radiation therapy for older adults with glioblastoma: radical treatment, palliative treatment, or no treatment at all?Predictive biomarkers investigated in glioblastoma.Glioblastoma care in the elderly.Epigenetic alternations and cancer chemotherapy response.Glioblastoma multiforme (GBM) in the elderly: initial treatment strategy and overall survival.Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.The predictive but not prognostic value of MGMT promoter methylation status in elderly glioblastoma patients: a meta-analysis.Improved hippocampal dose with reduced margin radiotherapy for glioblastoma multiforme.Management and treatment recommendations for World Health Organization Grade III and IV gliomas.Endoscopy-verified occult subependymal dissemination of glioblastoma and brain metastasis undetected by MRI: prognostic significance.Elevated IQGAP1 and CDC42 levels correlate with tumor malignancy of human glioma.Is the prognostic significance of O6-methylguanine- DNA methyltransferase promoter methylation equally important in glioblastomas of patients from different continents? A systematic review with meta-analysis.Are we ready to demystify age in glioblastoma? Or does older age matter in glioblastoma?The prognosis of MGMT promoter methylation in glioblastoma patients of different race: a meta-analysis.MGMT promoter methylation as a potential prognostic marker for acute leukemia.Glioblastoma in elderly patients: solid conclusions built on shifting sand?Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.BICD1 expression, as a potential biomarker for prognosis and predicting response to therapy in patients with glioblastomas.Primary brain tumors in the elderly population.

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P2860

Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma.

http://www.wikidata.org/entity/Q37425078

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2009 nî lūn-bûn

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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type

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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Mgmt methylation is a prognost ...... newly diagnosed glioblastoma.

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A J Iafrate

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D N Louis

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E R Gerstner

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P2860

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity.

O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

Treatment of glioblastoma multiforme in elderly patients. Clinico-therapeutic remarks in 22 patients older than 80 years.

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

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