Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated β-cells that is associated with irreversible DNA damage.
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Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosisFoxO1 and SIRT1 regulate beta-cell responses to nitric oxideCirculating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.Nitric oxide induces ataxia telangiectasia mutated (ATM) protein-dependent γH2AX protein formation in pancreatic β cells.12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.A plastic stabilizer dibutyltin dilaurate induces subchronic neurotoxicity in ratsDeoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines.Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agentsDifferential responses of pancreatic β-cells to ROS and RNS.Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cellsNitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage ResponseDo β-cells generate peroxynitrite in response to cytokine treatment?The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis.Involvement of the RNA-binding protein ARE/poly(U)-binding factor 1 (AUF1) in the cytotoxic effects of proinflammatory cytokines on pancreatic beta cells.Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide-Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells.
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P2860
Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated β-cells that is associated with irreversible DNA damage.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Nitric oxides mediates a shift ...... with irreversible DNA damage.
@en
Nitric oxides mediates a shift ...... with irreversible DNA damage.
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type
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Nitric oxides mediates a shift ...... with irreversible DNA damage.
@en
Nitric oxides mediates a shift ...... with irreversible DNA damage.
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Nitric oxides mediates a shift ...... with irreversible DNA damage.
@en
Nitric oxides mediates a shift ...... with irreversible DNA damage.
@nl
P2093
P2860
P1476
Nitric oxides mediates a shift ...... d with irreversible DNA damage
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John A Corbett
Kari T Chambers
Katherine J Hughes
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P304
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10.1152/AJPENDO.00214.2009
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2009-09-08T00:00:00Z