The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.
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Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-SAnimal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and DivergencesThe epithelial sodium channel δ-subunit: new notes for an old songAtomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC)Expression and purification of the alpha subunit of the epithelial sodium channel, ENaC.Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites.δ ENaC: a novel divergent amiloride-inhibitable sodium channelProteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites.Glioma-specific cation conductance regulates migration and cell cycle progressionPlasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel.Bile acids potentiate proton-activated currents in Xenopus laevis oocytes expressing human acid-sensing ion channel (ASIC1a).Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling.Activation of the Human Epithelial Sodium Channel (ENaC) by Bile Acids Involves the Degenerin Site.δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes.A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition.Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC).A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect.Conserved cysteines in the finger domain of the epithelial Na+ channel α and γ subunits are proximal to the dynamic finger-thumb domain interface.Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro.Incorporation of the δ-subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in Xenopus laevis.
P2860
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P2860
The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 28 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The delta-subunit of the epith ...... s proteolytic ENaC activation.
@en
The delta-subunit of the epithelial sodium channel
@nl
type
label
The delta-subunit of the epith ...... s proteolytic ENaC activation.
@en
The delta-subunit of the epithelial sodium channel
@nl
prefLabel
The delta-subunit of the epith ...... s proteolytic ENaC activation.
@en
The delta-subunit of the epithelial sodium channel
@nl
P2093
P2860
P356
P1476
The delta-subunit of the epith ...... s proteolytic ENaC activation.
@en
P2093
Bettina Krueger
Christoph Korbmacher
Robert Rauh
Silke Haerteis
P2860
P304
29024-29040
P356
10.1074/JBC.M109.018945
P407
P577
2009-08-28T00:00:00Z