Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.
about
Advanced glycation end-products induce calpain-mediated degradation of ezrinMerlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleusA neuronal function of the tumor suppressor protein merlinActin binding proteins in blood-testis barrier functionRole of protein kinase C isoforms in bile formation and cholestasisFeedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axisNF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.LRCH proteins: a novel family of cytoskeletal regulatorsTRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin CortexStructural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 functionOpen conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scatteringOrganizing the cell cortex: the role of ERM proteinsMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalCurrent issues in malignant pleural mesothelioma evaluation and managementE-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.Childhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies.A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas.mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.Merlin/ERM proteins establish cortical asymmetry and centrosome position.The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.The molecular biology of vestibular schwannomas and its association with hearing loss: a review.Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants.Ezrin-mediated apical integrity is required for intestinal homeostasis.Repulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins.The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway.A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells.Merlin is required for coordinating proliferation of two stem cell lineages in the Drosophila testis.The nematode homologue of Mediator complex subunit 28, F28F8.5, is a critical regulator of C. elegans development.ERM proteins at a glanceNf2/Merlin controls progenitor homeostasis and tumorigenesis in the liverCoordinate-based colocalization analysis of single-molecule localization microscopy data.Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.Using the neurofibromatosis tumor predisposition syndromes to understand normal nervous system development.Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling.The Legionella pneumophila Chaperonin - An Unusual Multifunctional Protein in Unusual Locations.FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function.
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P2860
Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@en
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@nl
type
label
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@en
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@nl
prefLabel
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@en
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@nl
P2860
P1476
Merlin and the ERM proteins--r ...... signaling at the cell cortex.
@en
P2093
Andrea I McClatchey
Richard G Fehon
P2860
P304
P356
10.1016/J.TCB.2009.02.006
P577
2009-04-01T00:00:00Z