Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.
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Protein kinase C-ζ mediates lung injury induced by diesel exhaust particlesLow-concentration ozone reacts with plasmalogen glycerophosphoethanolamine lipids in lung surfactant.Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycinLysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis.Lpa2 is a negative regulator of both dendritic cell activation and murine models of allergic lung inflammation.Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium.Extracellular signal-regulated kinase (ERK) regulates cortactin ubiquitination and degradation in lung epithelial cellsLysophosphatidic acid (LPA) and its receptors: role in airway inflammation and remodeling.Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cellsAutotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.Polyunsaturated lysophosphatidic acid as a potential asthma biomarker.Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.Rapid and reversible enhancement of blood-brain barrier permeability using lysophosphatidic acid.Alpha-1 antitrypsin reduces severity of pseudomonas pneumonia in mice and inhibits epithelial barrier disruption and pseudomonas invasion of respiratory epithelial cellsRole of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma.Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.Mathematical Modeling of Streptococcus pneumoniae Colonization, Invasive Infection and Treatment.AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-CadherinAdult Lysophosphatidic Acid Receptor 1-Deficient Rats with Hyperoxia-Induced Neonatal Chronic Lung Disease Are Protected against Lipopolysaccharide-Induced Acute Lung Injury.Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense.The deubiquitinating enzyme USP48 stabilizes TRAF2 and reduces E-cadherin-mediated adherens junctions.Lysophosphatidic Acid Receptor 1 Is Important for Intestinal Epithelial Barrier Function and Susceptibility to Colitis.Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury.Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury.
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Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Lysophosphatidic acid enhances ...... er disruption and lung injury.
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P2093
P2860
P356
P1476
Lysophosphatidic acid enhances ...... er disruption and lung injury.
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Donghong He
Ernst Wm Spannhake
Julian Solway
Paul Kogut
Peter V Usatyuk
Viswanathan Natarajan
Yutong Zhao
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P304
24123-24132
P356
10.1074/JBC.M109.007393
P407
P577
2009-07-08T00:00:00Z