SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis.
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SIRT1 and Kidney FunctionSirtuins and Cancer: Role in the Epithelial-Mesenchymal TransitionMechanisms of TGFβ-Induced Epithelial-Mesenchymal TransitionSIRT1: A Novel Target for the Treatment of Muscular DystrophiesSirtuins in epigenetic regulationInhibitory effect of Ginkgol C17:1 on the biological behavior of tumor cells.Enhanced expression and phosphorylation of Sirt7 activates smad2 and ERK signaling and promotes the cardiac fibrosis differentiation upon angiotensin-II stimulationInduction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activityβ2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cells.Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancerRole of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasisAlisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cellsSIRT1 catalytic activity has little effect on tumor formation and metastases in a mouse model of breast cancer.SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumorsGlobal profiling of metabolic adaptation to hypoxic stress in human glioblastoma cells.Sirtuin 1: A Target for Kidney Diseases.The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathySIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.Cross Talk Mechanism among EMT, ROS, and Histone Acetylation in Phorbol Ester-Treated Human Breast Cancer MCF-7 Cells.Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars.Transcriptional repression of SIRT1 by protein inhibitor of activated STAT 4 (PIAS4) in hepatic stellate cells contributes to liver fibrosis.Resveratrol attenuates renal injury and fibrosis by inhibiting transforming growth factor-β pathway on matrix metalloproteinase 7.IL-8 induces the epithelial-mesenchymal transition of renal cell carcinoma cells through the activation of AKT signaling.The emerging and diverse roles of sirtuins in cancer: a clinical perspective.SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis.Calorie restriction and sirtuins revisitedO-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway.Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway.Matrix Metalloproteinases-7 and Kidney Fibrosis.SIRT1 promotes metastasis of human osteosarcoma cells.Mechanisms of initiation and progression of intestinal fibrosis in IBD.Oncogenic role of SIRT1 associated with tumor invasion, lymph node metastasis, and poor disease-free survival in triple negative breast cancer.SIRT1 induces tumor invasion by targeting epithelial mesenchymal transition-related pathway and is a prognostic marker in triple negative breast cancer.Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer.Sirtuin and metabolic kidney disease.Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells.SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis.SIRT1 promotes the proliferation and metastasis of human pancreatic cancer cells.Lysophosphatidic Acid Promotes Epithelial to Mesenchymal Transition in Ovarian Cancer Cells by Repressing SIRT1.
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SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
@en
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
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type
label
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
@en
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
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prefLabel
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
@en
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
@nl
P2093
P2860
P1433
P1476
SIRT1 suppresses the epithelia ...... metastasis and organ fibrosis.
@en
P2093
Eric L Bell
Eric O Williams
Jing Jing Gong
Leonard Guarente
Michael Bonkowski
Petra Simic
P2860
P304
P356
10.1016/J.CELREP.2013.03.019
P577
2013-04-11T00:00:00Z