An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion
about
The CD9/CD81 tetraspanin complex and tetraspanin CD151 regulate α3β1 integrin-dependent tumor cell behaviors by overlapping but distinct mechanismsBiochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decadeFree edges in epithelial cell sheets stimulate epidermal growth factor receptor signaling.The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation.RGD-Binding Integrins in Head and Neck Cancers.Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kBSuppression of integrin alpha3beta1 in breast cancer cells reduces cyclooxygenase-2 gene expression and inhibits tumorigenesis, invasion, and cross-talk to endothelial cells.Regulation of fibulin-2 gene expression by integrin α3β1 contributes to the invasive phenotype of transformed keratinocytesFree edges in epithelia as cues for motility.Translationally controlled tumor protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasisIntegrin α3β1 signaling through MEK/ERK determines alternative polyadenylation of the MMP-9 mRNA transcript in immortalized mouse keratinocytesIntegrin α3β1 as a breast cancer targetα6β4 integrin, a master regulator of expression of integrins in human keratinocytes.Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cellsKLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9.Integrin α3β1 controls mRNA splicing that determines Cox-2 mRNA stability in breast cancer cells.Sohlh2 inhibits human ovarian cancer cell invasion and metastasis by transcriptional inactivation of MMP9.Determination of alternate splicing events using the Affymetrix Exon 1.0 ST arraysAlpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3.Integrins and p53 pathways in glioblastoma resistance to temozolomide.Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis.Association of ITGA3 gene polymorphisms with susceptibility and clinicopathological characteristics of osteosarcoma.
P2860
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P2860
An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An immortalization-dependent s ...... to enhance tumor cell invasion
@en
An immortalization-dependent s ...... o enhance tumor cell invasion.
@nl
type
label
An immortalization-dependent s ...... to enhance tumor cell invasion
@en
An immortalization-dependent s ...... o enhance tumor cell invasion.
@nl
prefLabel
An immortalization-dependent s ...... to enhance tumor cell invasion
@en
An immortalization-dependent s ...... o enhance tumor cell invasion.
@nl
P2860
P1433
P1476
An immortalization-dependent s ...... to enhance tumor cell invasion
@en
P2093
C Michael DiPersio
John M Lamar
P2860
P304
P356
10.1158/0008-5472.CAN-08-1080
P407
P577
2008-09-01T00:00:00Z