Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
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Nutraceutical use in late-stage cancer.Enterohepatic recirculation of bioactive ginger phytochemicals is associated with enhanced tumor growth-inhibitory activity of ginger extract.Bioavailability challenges associated with development of anti-cancer phenolics.6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation.Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells.Suites of terpene synthases explain differential terpenoid production in ginger and turmeric tissues.Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approachA proteomic analysis of Curcuma comosa Roxb. rhizomes.Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways.Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes.Cysteine-conjugated metabolite of ginger component [6]-shogaol serves as a carrier of [6]-shogaol in cancer cells and in mice.Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity.Antioxidant and Anti-inflammatory Activities of Butanol Extract of Melaleuca leucadendron L.Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.Ginger phytochemicals exhibit synergy to inhibit prostate cancer cell proliferation.[6]-shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2.Update on the chemopreventive effects of ginger and its phytochemicals.Cancer Chemoprevention Effects of Ginger and its Active Constituents: Potential for New Drug Discovery.Anti-inflammatory effects of the Zingiber officinale roscoe constituent 12-dehydrogingerdione in lipopolysaccharide-stimulated Raw 264.7 cells.Anticancer activity of rice callus suspension culture.Evaluation of antimutagenic and protective effects of Parkinsonia aculeata L. leaves against H2O2 induced damage in pBR322 DNA.The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling.Antioxidant Activity of Spices and Their Impact on Human Health: A ReviewIsolation and characterization of cyclo-(tryptophanyl-prolyl) and chloramphenicol from Streptomyces sp. SUK 25 with antimethicillin-resistant Staphylococcus aureus activity.Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model.Impact of Phytochemicals and Dietary Patterns on Epigenome and Cancer.
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P2860
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 07 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@en
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@nl
type
label
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@en
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@nl
prefLabel
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@en
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@nl
P2093
P356
P1433
P1476
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
@en
P2093
Hye-Kyung Na
Joydeb Kumar Kundu
Young-Joon Surh
P304
P356
10.1159/000212750
P577
2009-04-07T00:00:00Z