Two analogues of fenarimol show curative activity in an experimental model of Chagas disease.
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Translational challenges of animal models in Chagas disease drug development: a reviewA new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging4-Aminopyridyl-Based CYP51 Inhibitors as Anti- Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo PotencyDrug strategies targeting CYP51 in neglected tropical diseasesBinding mode and potency of N-indolyloxopyridinyl-4-aminopropanyl-based inhibitors targeting Trypanosoma cruzi CYP51.Lead identification to clinical candidate selection: drugs for Chagas disease.Enantiomers of nifurtimox do not exhibit stereoselective anti-Trypanosoma cruzi activity, toxicity, or pharmacokinetic properties.Therapeutical approaches under investigation for treatment of Chagas disease.Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruziApplications of Palladium-Catalyzed C-N Cross-Coupling Reactions.In vitro drug susceptibility of two strains of the wildlife trypanosome, Trypanosoma copemani: A comparison with Trypanosoma cruziExperimental and Clinical Treatment of Chagas Disease: A Review.Electrochemically Enabled, Nickel-Catalyzed Amination.Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.
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P2860
Two analogues of fenarimol show curative activity in an experimental model of Chagas disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@en
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@nl
type
label
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@en
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@nl
prefLabel
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@en
Two analogues of fenarimol sho ...... ental model of Chagas disease.
@nl
P2093
P2860
P356
P1476
Two analogues of fenarimol sho ...... mental model of Chagas disease
@en
P2093
Adriana Botero
Andrea Khong
Catherine Perez
David M Shackleford
Eileen Ryan
Eric Chatelain
Francis C K Chiu
Ivan Scandale
Jason H Chaplin
Julia Morizzi
P2860
P304
10158-10170
P356
10.1021/JM401610C
P407
P577
2013-12-04T00:00:00Z