Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats.

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Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.

P2860

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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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name

Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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type

Item

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Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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P1476

Selective antagonism of TRPA1 ...... ical hypersensitivity in rats.

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P2093

Andy D Weyer

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Beth D Youngblood

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Bryan D Moyer

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Cheryl L Stucky

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Kenneth D Wild

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Laurie Schenkel

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Maosheng Zhang

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Melanie Cooke

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Narender R Gavva

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Ruoyuan Yin

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P2860

Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists

How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.

A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome

TRPA1 mediates mechanical sensitization in nociceptors during inflammation

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain

Urate crystal induced inflammation and joint pain are reduced in transient receptor potential ankyrin 1 deficient mice--potential role for transient receptor potential ankyrin 1 in gout

TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats

TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury.

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scholarly article

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10.1177/1744806916677761

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2016-11-29T00:00:00Z

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27899696

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5131813

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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats.

about

P2860

P2860

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats.

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