about
Insulin in the brain: there and back againNotch signaling as a novel regulator of metabolismHigh energy diets-induced metabolic and prediabetic painful polyneuropathy in ratsCurrent views on type 2 diabetes.Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in miceTLR4 and Insulin Resistance.Targeted inactivation of GPR26 leads to hyperphagia and adiposity by activating AMPK in the hypothalamus.Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.Activation of K(ATP) channels suppresses glucose production in humans.Pancreatic function, type 2 diabetes, and metabolism in aging.Year in diabetes 2012: The diabetes tsunami.Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats.Pigment epithelium-derived factor (PEDF) peptide eye drops reduce inflammation, cell death and vascular leakage in diabetic retinopathy in Ins2(Akita) mice.UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose ResponsivenessLeptin, diabetes, and the brainVanilloid receptors--do they have a role in whole body metabolism? Evidence from TRPV1.Brain-liver connections: role of the preautonomic PVN neurons.Olanzapine activates hepatic mammalian target of rapamycin: new mechanistic insight into metabolic dysregulation with atypical antipsychotic drugs.Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism.Peptide hormones regulating appetite--focus on neuroimaging studies in humans.Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery.CNS regulation of plasma cholesterol.Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose productionCNS drug targeting: have we travelled in right path?Molecular Profiling of Human Induced Pluripotent Stem Cell-Derived Hypothalamic Neurones Provides Developmental Insights into Genetic Loci for Body Weight Regulation.Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease.Discovery of a potent thiadiazole class of histamine h3 receptor antagonist for the treatment of diabetesDeoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat.Central Regulation of Glucose Production May Be Impaired in Type 2 Diabetes.GLP-1 treatment reduces endogenous insulin resistance via activation of central GLP-1 receptors in mice fed a high-fat diet.Overactivity of Liver-Related Neurons in the Paraventricular Nucleus of the Hypothalamus: Electrophysiological Findings in db/db Mice.Feeding signals to the hungry mind.Effect of histamine receptors agonists or antagonists administered intracerebroventricularly and intrathecally on the blood glucose level in immobilization stress model
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting the CNS to treat type 2 diabetes.
@en
Targeting the CNS to treat type 2 diabetes.
@nl
type
label
Targeting the CNS to treat type 2 diabetes.
@en
Targeting the CNS to treat type 2 diabetes.
@nl
prefLabel
Targeting the CNS to treat type 2 diabetes.
@en
Targeting the CNS to treat type 2 diabetes.
@nl
P2093
P2860
P356
P1476
Targeting the CNS to treat type 2 diabetes.
@en
P2093
Darleen A Sandoval
Randy J Seeley
Silvana Obici
P2860
P2888
P304
P356
10.1038/NRD2874
P577
2009-05-01T00:00:00Z
P5875
P6179
1003896074