Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. - Wikidata - wikimedia - TriplyDB

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

http://www.wikidata.org/entity/Q37465606

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Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development Novel therapeutics for Alzheimer's disease: an update Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway Epigenetic oxidative redox shift (EORS) theory of aging unifies the free radical and insulin signaling theories.Comparative ultrastructural analysis of mitochondria in the CA1 and CA3 hippocampal pyramidal cells following global ischemia in Mongolian gerbils.Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies.Neuroprotective strategies involving ROS in Alzheimer disease.Frontiers in Alzheimer's disease therapeutics.Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies.Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease.Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.Mitochondria: a therapeutic target in neurodegeneration D-galactose induces a mitochondrial complex I deficiency in mouse skeletal muscle: potential benefits of nutrient combination in ameliorating muscle impairment.Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling Implication of the nutritional and nonnutritional factors in the context of preservation of cognitive performance in patients with dementia/depression and Alzheimer disease.Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders.Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease.Age-Induced Alterations in Hippocampal Function and Metabolism.Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor Deprivation In vivo and in vitro assessment of brain bioenergetics in aging rats.Mitochondrial modulators improve lipid composition and attenuate memory deficits in experimental model of Huntington's disease.Dihydromyricetin Improves Hypobaric Hypoxia-Induced Memory Impairment via Modulation of SIRT3 Signaling.Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration.Neurodegeneration of Drosophila drop-dead mutants is associated with hypoxia in the brain.Altered heavy metals and transketolase found in autistic spectrum disorder.Age-related defects in short-term plasticity are reversed by acetyl-L-carnitine at the mouse calyx of Held.Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats.

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Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

http://www.wikidata.org/entity/Q37465606

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article científic

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bilimsel makale

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scientific article published on 28 March 2008

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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J.1582-4934.2008.00324.X

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Journal of Cellular and Molecular Medicine

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Neuronal mitochondrial amelior ...... and lipoic acid to aged rats.

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Arlan G Richardson

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Bruce N Ames

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Eldar Gasimov

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Gerardo J Pacheco

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Gjumrakch Aliev

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Jiankang Liu

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Justin C Shenk

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Kathryn Fischbach

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Mark E Obrenovich

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Walter F Ward

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P2860

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

Normal immune function in young and old DNA polymerase-beta deficient mice

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

Extension of murine life span by overexpression of catalase targeted to mitochondria

Oxidative stress, caloric restriction, and aging

Mechanisms of aging: an appraisal of the oxidative stress hypothesis.

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

Protein oxidation and aging.

Age-related changes in lymphocyte development and function.

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10.1111/J.1582-4934.2008.00324.X

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