Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element.
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Evidence for interaction between human PRUNE and nm23-H1 NDPKinaseMetastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expressionNM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III13'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activityNeuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosisUV-responsive genes of arabidopsis revealed by similarity to the Gcn4-mediated UV response in yeast.NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.Identification of a mitochondrial nucleoside diphosphate kinase from the green alga Dunaliella tertiolecta.Differential expression of nm23 genes in adult mouse dorsal root ganglia.The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages.Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegansChemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule.Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair functionDENN domain proteins: regulators of Rab GTPases.Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation.Single strand DNA specificity analysis of human nucleoside diphosphate kinase B.Xenopus NM23-X4 regulates retinal gliogenesis through interaction with p27Xic1.Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells.The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.NM23/NDPK proteins in transcription regulatory functions and chromatin modulation: emerging trends.Nuclear functions of NME proteins.A critical evaluation of biochemical activities reported for the nucleoside diphosphate kinase/Nm23/Awd family proteins: opportunities and missteps in understanding their biological functions.The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities.
P2860
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P2860
Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1996
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@en
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@nl
type
label
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@en
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@nl
prefLabel
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@en
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@nl
P2093
P2860
P356
P1476
Mutational analysis of NM23-H2 ...... of a c-myc regulatory element.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.14.6892
P407
P577
1996-07-01T00:00:00Z