Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition
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Angiotensin II during Experimentally Simulated Central HypovolemiaPressure natriuresis and the renal control of arterial blood pressureInhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertensionRenal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retentionRenal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II.Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis.Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbsRole of caveolin 1 in AT1a receptor-mediated uptake of angiotensin II in the proximal tubule of the kidney.Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.Angiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation.STE20/SPS1-related proline/alanine-rich kinase (SPAK) is critical for sodium reabsorption in isolated, perfused thick ascending limb.Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevationShort-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron.Norepinephrine-evoked salt-sensitive hypertension requires impaired renal sodium chloride cotransporter activity in Sprague-Dawley rats.Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced HypertensionMaintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During HypertensionTraditional and emerging roles for the SLC9 Na+/H+ exchangers.Collecting Duct Prorenin Receptor Knockout Reduces Renal Function, Increases Na+ Excretion and Mitigates renal Responses in ANGII induced hypertensive mice.Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice.Everything we always wanted to know about furosemide but were afraid to ask.Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension.Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies.The innervation of the kidney in renal injury and inflammation: a cause and consequence of deranged cardiovascular control.Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure-Hypertension and the Proximal Tubule.Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.The effect of captopril and losartan on the electrophysiology of myocardial cells of myocardial ischemia rats.Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors.SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone.Body mass-specific Na+, K+-ATPase activity in the medullary thick ascending limb - implications for species-dependent urine concentrating mechanisms.Collecting duct (pro)renin receptor targets ENaC to mediate angiotensin II-induced hypertension.Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance.Responses of distal nephron Na+ transporters to acute volume depletion and hyperkalemia.Distal convoluted tubule.Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats.Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation
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Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differential regulation of Na+ ...... eracted by proximal inhibition
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Differential regulation of Na+ ...... racted by proximal inhibition.
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Differential regulation of Na+ ...... eracted by proximal inhibition
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Differential regulation of Na+ ...... racted by proximal inhibition.
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Differential regulation of Na+ ...... eracted by proximal inhibition
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Differential regulation of Na+ ...... racted by proximal inhibition.
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P2093
P2860
P1476
Differential regulation of Na+ ...... eracted by proximal inhibition
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P2093
Alicia A McDonough
Donna H Lee
Eric Delpire
Mien T X Nguyen
P2860
P304
P356
10.1152/AJPRENAL.00183.2013
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2013-05-29T00:00:00Z