HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML
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Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndromeMcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia.EZH2 in normal and malignant hematopoiesis.Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.Minireview: role of orphan nuclear receptors in cancer and potential as drug targetsTargeting prohibitins induces apoptosis in acute myeloid leukemia cells.Nuclear receptor 4A (NR4A) family - orphans no more.Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults.Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia.Significance of Inactivated Genes in Leukemia: Pathogenesis and PrognosisEpigenetic regulation of the NR4A orphan nuclear receptor NOR1 by histone acetylation.Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.Histone Deacetylase Inhibitor Enhances the Efficacy of MEK Inhibitor through NOXA-Mediated MCL1 Degradation in Triple-Negative and Inflammatory Breast Cancer.Nuclear receptor nur77 promotes cerebral cell apoptosis and induces early brain injury after experimental subarachnoid hemorrhage in rats.
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HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 December 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HDAC inhibition by SNDX-275 (E ...... pro-apoptotic proteins in AML
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HDAC inhibition by SNDX-275
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type
label
HDAC inhibition by SNDX-275 (E ...... pro-apoptotic proteins in AML
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HDAC inhibition by SNDX-275
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prefLabel
HDAC inhibition by SNDX-275 (E ...... pro-apoptotic proteins in AML
@en
HDAC inhibition by SNDX-275
@nl
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P921
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HDAC inhibition by SNDX-275 (E ...... pro-apoptotic proteins in AML
@en
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I J Samudio
M Andreeff
M Konopleva
O Conneely
V R Ruvolo
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P2888
P304
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10.1038/LEU.2012.366
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2012-12-18T00:00:00Z