Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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HDAC and Ku70 axis- an effective target for apoptosis induction by a new 2-cyano-3-oxo-1,9-dien glycyrrhetinic acid analogue.

P2860

Q55076389-D32E65E4-2117-44E5-A777-AB58411088F8

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Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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http://www.wikidata.org/entity/Q50911306

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

@en

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

@nl

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Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

@en

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

@nl

P1476

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer

@en

P2093

Eric Eldering

http://www.w3.org/2001/XMLSchema#string

Martine Amiot

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P2860

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

BH3 domains other than Bim and Bid can directly activate Bax/Bak

Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

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767-779

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scholarly article

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10.1080/14728222.2017.1349754

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English

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P478

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Jeroen E Guikema

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2017-07-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28670929

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apoptotic process

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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P2860

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

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type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921