Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease.
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β-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro modelHigh-level genomic integration, epigenetic changes, and expression of sleeping beauty transgeneErythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells.Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.Restoration of dystrophin expression using the Sleeping Beauty transposon.Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposonGenomic analysis of Sleeping Beauty transposon integration in human somatic cells.Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice.β-globin matrix attachment region improves stable genomic expression of the Sleeping Beauty transposon.Physiological and tissue-specific vectors for treatment of inherited diseases.The expanding universe of transposon technologies for gene and cell engineering.The Sleeping Beauty transposon system for clinical applications.Recent developments in transposon-mediated gene therapy.Long-term and efficient expression of human β-globin gene in a hematopoietic cell line using a new site-specific integrating non-viral system.A human/murine chimeric fab antibody neutralizes anthrax lethal toxin in vitro.Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.
P2860
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P2860
Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 May 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Erythroid-specific expression ...... poson for Sickle cell disease.
@en
Erythroid-specific expression ...... poson for Sickle cell disease.
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type
label
Erythroid-specific expression ...... poson for Sickle cell disease.
@en
Erythroid-specific expression ...... poson for Sickle cell disease.
@nl
prefLabel
Erythroid-specific expression ...... poson for Sickle cell disease.
@en
Erythroid-specific expression ...... poson for Sickle cell disease.
@nl
P2093
P2860
P356
P1433
P1476
Erythroid-specific expression ...... poson for Sickle cell disease.
@en
P2093
Betsy T Kren
Chang Won Park
Clifford J Steer
Jianhui Zhu
Phillip Y-P Wong
Rasim Bilgim
P2860
P304
P356
10.1021/BI6024484
P407
P577
2007-05-18T00:00:00Z