Unlocking the molecular secrets of sodium-coupled transporters.
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New technologies for 21st century plant scienceDesigning modulators of monoamine transporters using virtual screening techniquesInverted topologies in membrane proteins: a mini-reviewVisualizing functional motions of membrane transporters with molecular dynamics simulationsHow LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transportersComplete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycleUnveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic ResiduesModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueStructure of a prokaryotic virtual proton pump at 3.2 Å resolutionTransport mechanism of a bacterial homologue of glutamate transporters.Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2The mechanism of sodium and substrate release from the binding pocket of vSGLTMolecular basis of substrate-induced permeation by an amino acid antiporterCrystal structure of a phosphorylation-coupled saccharide transporterSubstrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologueInsights into transport mechanism from LeuT engineered to transport tryptophanStructures of a Na+-coupled, substrate-bound MATE multidrug transporterX-ray structures of LeuT in substrate-free outward-open and apo inward-open statesCrystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 ÅMolecular mechanism of ligand recognition by membrane transport protein, Mhp1Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transportersMolecular and evolutionary insights into the structural organization of cation chloride cotransportersSimple screening method for improving membrane protein thermostabilitySkeletal muscle-specific calpain is an intracellular Na+-dependent proteaseA family of diatom-like silicon transporters in the siliceous loricate choanoflagellatesStructural model of the anion exchanger 1 (SLC4A1) and identification of transmembrane segments forming the transport site.Conformational Changes in Two Inter-Helical Loops of Mhp1 Membrane Transporter.Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy.A gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporterToward the fourth dimension of membrane protein structure: insight into dynamics from spin-labeling EPR spectroscopyA single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters.Two mechanisms of ion selectivity in protein binding sitesStructural insights into the activation mechanism of melibiose permease by sodium binding.Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.NhaA Na+/H+ antiporter mutants that hardly react to the membrane potential.Structure and hydration of membranes embedded with voltage-sensing domains.Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension.Molecular modeling and ligand docking for solute carrier (SLC) transportersTransmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.
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Unlocking the molecular secrets of sodium-coupled transporters.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Unlocking the molecular secrets of sodium-coupled transporters.
@en
Unlocking the molecular secrets of sodium-coupled transporters.
@nl
type
label
Unlocking the molecular secrets of sodium-coupled transporters.
@en
Unlocking the molecular secrets of sodium-coupled transporters.
@nl
prefLabel
Unlocking the molecular secrets of sodium-coupled transporters.
@en
Unlocking the molecular secrets of sodium-coupled transporters.
@nl
P2093
P356
P1433
P1476
Unlocking the molecular secrets of sodium-coupled transporters
@en
P2093
Chayne L Piscitelli
Eric Gouaux
Harini Krishnamurthy
P2888
P304
P356
10.1038/NATURE08143
P407
P577
2009-05-01T00:00:00Z
P5875
P6179
1043485382