Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier.
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Visualization of targeted transduction by engineered lentiviral vectorsInsulin in the brain: there and back againDendrimer advances for the central nervous system delivery of therapeuticsProtein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 diseaseVisualization of DC-SIGN-mediated entry pathway of engineered lentiviral vectors in target cellsGDNF-transfected macrophages produce potent neuroprotective effects in Parkinson's disease mouse modelInflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyreneReplacing the enzyme alpha-L-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I.Characteristics of compounds that cross the blood-brain barrierGenistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type IICorticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier.Mouse models of neurological disorders: a view from the blood-brain barrier.Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse.Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII.A breach in the blood-brain barrier.Agile delivery of protein therapeutics to CNSGalactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in miceHuman immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrierSystemic administration of tripeptidyl peptidase I in a mouse model of late infantile neuronal ceroid lipofuscinosis: effect of glycan modification.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Enhanced real-time monitoring of adeno-associated virus trafficking by virus-quantum dot conjugatesInitial fate of prions upon peripheral infection: half-life, distribution, clearance, and tissue uptake.Cell replacement therapy in neurological disease.Large-volume intrathecal enzyme delivery increases survival of a mouse model of late infantile neuronal ceroid lipofuscinosis.Exosomes as drug delivery vehicles for Parkinson's disease therapyVisualization of intracellular pathways of engineered baculovirus in mammalian cellsTargeted delivery of proteins across the blood-brain barrier.Glia Disease and Repair-RemyelinationAlpha Adrenergic Induction of Transport of Lysosomal Enzyme across the Blood-Brain Barrier.Engaging neuroscience to advance translational research in brain barrier biology.Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptorProgenitor cell-based treatment of the pediatric myelin disordersIntravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis.Biochemical evidence for superior correction of neuronal storage by chemically modified enzyme in murine mucopolysaccharidosis VII.Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis miceChemically modified beta-glucuronidase crosses blood-brain barrier and clears neuronal storage in murine mucopolysaccharidosis VII.Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptorEngineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrierPharmacologic manipulation of lysosomal enzyme transport across the blood-brain barrier.A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.
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Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 16 August 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Developmentally regulated mann ...... cross the blood-brain barrier.
@en
Developmentally regulated mann ...... cross the blood-brain barrier.
@nl
type
label
Developmentally regulated mann ...... cross the blood-brain barrier.
@en
Developmentally regulated mann ...... cross the blood-brain barrier.
@nl
prefLabel
Developmentally regulated mann ...... cross the blood-brain barrier.
@en
Developmentally regulated mann ...... cross the blood-brain barrier.
@nl
P2093
P2860
P356
P1476
Developmentally regulated mann ...... cross the blood-brain barrier.
@en
P2093
Akihiko Urayama
Jeffrey H Grubb
William S Sly
P2860
P304
12658-12663
P356
10.1073/PNAS.0405042101
P407
P577
2004-08-16T00:00:00Z