Axon guidance proteins: novel therapeutic targets for ALS?
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ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseSemaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosisOlfactory ensheathing cell transplantation into spinal cord prolongs the survival of mutant SOD1(G93A) ALS rats through neuroprotection and remyelination.Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis.Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.Somatic and axonal LIGHT signaling elicit degenerative and regenerative responses in motoneurons, respectively.Progress in therapy development for amyotrophic lateral sclerosisDelayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortexNeuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.New therapeutic targets for amyotrophic lateral sclerosis.MICALs in control of the cytoskeleton, exocytosis, and cell death.Getting neural circuits into shape with semaphorins.MICAL, the flavoenzyme participating in cytoskeleton dynamicsGenome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells.The Axon Guidance Protein Semaphorin 3A Is Increased in the Motor Cortex of Patients With Amyotrophic Lateral Sclerosis.Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics.Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach.Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels.Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration.Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALSNitric oxide as a putative retinal axon pathfinding and target recognition cue in Xenopus laevis.Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction.
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Axon guidance proteins: novel therapeutic targets for ALS?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Axon guidance proteins: novel therapeutic targets for ALS?
@en
Axon guidance proteins: novel therapeutic targets for ALS?
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type
label
Axon guidance proteins: novel therapeutic targets for ALS?
@en
Axon guidance proteins: novel therapeutic targets for ALS?
@nl
prefLabel
Axon guidance proteins: novel therapeutic targets for ALS?
@en
Axon guidance proteins: novel therapeutic targets for ALS?
@nl
P1476
Axon guidance proteins: novel therapeutic targets for ALS?
@en
P2093
Ewoud R E Schmidt
R Jeroen Pasterkamp
P304
P356
10.1016/J.PNEUROBIO.2009.05.004
P577
2009-06-10T00:00:00Z