Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse.
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Proteome-wide lysine acetylation in cortical astrocytes and alterations that occur during infection with brain parasite Toxoplasma gondiiFundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite InterfaceA Putative Non-Canonical Ras-Like GTPase from P. falciparum: Chemical Properties and Characterization of the ProteinToxoplasma gondii Infection Induces High Mobility Group Box 1 Released from Mouse Macrophages.Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondiiEfficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9.The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii.A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCαCalmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondiiToxoplasma gondii GRA7-Induced TRAF6 Activation Contributes to Host Protective ImmunityAnalysis of Noncanonical Calcium-Dependent Protein Kinases in Toxoplasma gondii by Targeted Gene Deletion Using CRISPR/Cas9.Functional Analysis of the Role of Toxoplasma gondii Nucleoside Triphosphate Hydrolases I and II in Acute Mouse Virulence and Immune Suppression.Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.Rhoptry protein 5 (ROP5) Is a Key Virulence Factor in Neospora caninum.Toxoplasma Effectors Targeting Host Signaling and Transcription.Enhancement of the protective efficacy of a ROP18 vaccine against chronic toxoplasmosis by nasal route.The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading.Host-Toxoplasma gondii Coadaptation Leads to Fine Tuning of the Immune Response.Dense Granule Protein-7 (GRA-7) of Toxoplasma gondii inhibits viral replication in vitro and in vivo.Post-translational modifications as key regulators of apicomplexan biology: insights from proteome-wide studies.Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China.Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human CellsInducible Nitric Oxide Synthase Is a Key Host Factor for GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human ResponseFunctional Characterization of Dense Granule Proteins in RH Strain Using CRISPR-Cas9 SystemNADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
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Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@en
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@nl
type
label
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@en
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@nl
prefLabel
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@en
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@nl
P2093
P2860
P356
P1476
Toxoplasma GRA7 effector incre ...... acute virulence in the mouse.
@en
P2093
Aditi Alaganan
Keliang Tang
Qiuling Wang
Sarah J Fentress
P2860
P304
P356
10.1073/PNAS.1313501111
P407
P577
2014-01-03T00:00:00Z