Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2 - Wikidata - wikimedia - TriplyDB

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

http://www.wikidata.org/entity/Q37524401

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Embryonic stem cell and induced pluripotent stem cell: an epigenetic perspective Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapy Induced Pluripotent Stem Cells: Generation Strategy and Epigenetic Mystery behind Reprogramming Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis Active DNA demethylation in post-mitotic neurons: a reason for optimism Cytosine modifications in neurodevelopment and diseases Unlocking epigenetic codes in neurogenesis The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation Regulation of the Epigenome by Vitamin C Mechanism and function of oxidative reversal of DNA and RNA methylation Chromatin dynamics during cellular reprogramming Induced pluripotent stem cells in hematology: current and future applications Reprogramming of cell fate: epigenetic memory and the erasure of memories past Role of TET enzymes in DNA methylation, development, and cancer Concise Review: Induced Pluripotent Stem Cells as New Model Systems in Oncology DNA methylation and hydroxymethylation in stem cells WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation Toward pluripotency by reprogramming: mechanisms and application Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription Potential functional roles of DNA demethylation intermediates Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics.TET enzymes, TDG and the dynamics of DNA demethylation.Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription Mechanisms for enhancing cellular reprogramming Molecular control of induced pluripotency.New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines.NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.Mechanisms and models of somatic cell reprogramming.The combination of Tet1 with Oct4 generates high-quality mouse-induced pluripotent stem cells.Combinatorial modulation of signaling pathways reveals cell-type-specific requirements for highly efficient and synchronous iPSC reprogramming.Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome.CHD1L Regulated PARP1-Driven Pluripotency and Chromatin Remodeling During the Early-Stage Cell Reprogramming Effects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells.

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Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

http://www.wikidata.org/entity/Q37524401

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 2012

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

@en

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

@nl

type

label

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

@en

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

@nl

prefLabel

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

@en

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

@nl

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Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

@en

P2093

Alan Shih

http://www.w3.org/2001/XMLSchema#string

Asa Abeliovich

http://www.w3.org/2001/XMLSchema#string

Claudia A Doege

http://www.w3.org/2001/XMLSchema#string

David B Rhee

http://www.w3.org/2001/XMLSchema#string

Emily I Chen

http://www.w3.org/2001/XMLSchema#string

Paolo Guarnieri

http://www.w3.org/2001/XMLSchema#string

Ross L Levine

http://www.w3.org/2001/XMLSchema#string

Ryousuke Fujita

http://www.w3.org/2001/XMLSchema#string

Sara Nik

http://www.w3.org/2001/XMLSchema#string

Skylar Travis

http://www.w3.org/2001/XMLSchema#string

P2860

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Genome-scale DNA methylation maps of pluripotent and differentiated cells

DNA demethylation dynamics

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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scholarly article

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10.1038/NATURE11333

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7413

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488

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William B. Vanti

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2012-08-01T00:00:00Z

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230700133

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1044517222

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