Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers.

Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers.

Item
http://www.wikidata.org/entity/Q37524864
A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell diseaseA randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia.Alternative options for DNA-based experimental therapy of β-thalassemia.Evaluation of Novel Fetal Hemoglobin Inducer Drugs in Treatment of β-Hemoglobinopathy Disorders.A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.Acute effects of phenylbutyrate on glutamine, branched-chain amino acid and protein metabolism in skeletal muscles of rats.An oral HemokineTM, α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo.Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future ExpectationsKLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients
P2860

Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers.

Item
http://www.wikidata.org/entity/Q37524864
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 March 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Evaluation of safety and pharm ...... studies in healthy volunteers.
@en
Evaluation of safety and pharm ...... studies in healthy volunteers.
@nl
type
label
Evaluation of safety and pharm ...... studies in healthy volunteers.
@en
Evaluation of safety and pharm ...... studies in healthy volunteers.
@nl
prefLabel
Evaluation of safety and pharm ...... studies in healthy volunteers.
@en
Evaluation of safety and pharm ...... studies in healthy volunteers.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Evaluation of safety and pharm ...... studies in healthy volunteers
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932