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Mono- or double-site phosphorylation distinctly regulates the proapoptotic function of BaxCharge profile analysis reveals that activation of pro-apoptotic regulators Bax and Bak relies on charge transfer mediated allosteric regulationDirect Activation of Bax Protein for Cancer TherapyEscherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/Bak.The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion proteinAll-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent.Chemical glycosylation of cytochrome c improves physical and chemical protein stability.p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinomaMitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.Abieslactone induces cell cycle arrest and apoptosis in human hepatocellular carcinomas through the mitochondrial pathway and the generation of reactive oxygen speciesTrefoil Factor-3 (TFF3) Stimulates De Novo Angiogenesis in Mammary Carcinoma both Directly and Indirectly via IL-8/CXCR2.Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicityBH3-only protein Bim is associated with the degree of Helicobacter pylori-induced gastritis and is localized to the mitochondria of inflammatory cells in the gastric mucosaBim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer.Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.Synergic chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of SIRT1MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3aProtein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Tax contributes apoptosis resistance to HTLV-1-infected T cells via suppression of Bid and Bim expression.Natural compound Alternol induces oxidative stress-dependent apoptotic cell death preferentially in prostate cancer cells.Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.Histone deacetylase inhibitor potentiates chemotherapy-induced apoptosis through Bim upregulation in Burkitt's lymphoma cells.PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cells.Macrophage migration inhibitory factor deficiency protects pancreatic islets from palmitic acid-induced apoptosis.Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation.Guanylate cyclase activator YC-1 enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells via activation of apoptosis-related proteins.Diarylheptanoid hirsutenone enhances apoptotic effect of TRAIL on epithelial ovarian carcinoma cell lines via activation of death receptor and mitochondrial pathway.Insights into the structural stability of Bax from molecular dynamics simulations at high temperatures.Role of microRNAs in the resistance of colorectal cancer to chemoradiotherapy.PP1γ functionally augments the alternative splicing of CaMKIIδ through interaction with ASF.Stapled peptides as a new technology to investigate protein-protein interactions in human platelets.Oleanolic acid induces p53-dependent apoptosis via the ERK/JNK/AKT pathway in cancer cell lines in prostatic cancer xenografts in mice.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Bax activation by Bim?
@en
Bax activation by Bim?
@nl
type
label
Bax activation by Bim?
@en
Bax activation by Bim?
@nl
prefLabel
Bax activation by Bim?
@en
Bax activation by Bim?
@nl
P2860
P356
P1476
Bax activation by Bim?
@en
P2093
P E Czabotar
P M Colman
P2860
P2888
P304
P356
10.1038/CDD.2009.83
P577
2009-06-26T00:00:00Z