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Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression PathwaysClinical Overview of MDM2/X-Targeted TherapiesRegulation of Mutant p53 Protein ExpressionPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Silica Nanoparticles Induce Oxidative Stress and Autophagy but Not Apoptosis in the MRC-5 Cell LineNitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosisDisordered proteinaceous machinesDef defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradationMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.p53 vs. ISG15: stop, you're killing me.Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.Metabolic sensing by p53: keeping the balance between life and deathA functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.Targeting the ubiquitin-proteasome pathway with inorganic compounds to fight cancer: a challenge for the future.Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1(G93A) mice.Mitochondrial recoupling: a novel therapeutic strategy for cancer?The dose dependent in vitro responses of MCF-7 and MDA-MB-231 cell lines to extracts of Vatica diospyroides symington type SS fruit include effects on mode of cell deathGermline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.Bakuchiol Is a Phenolic Isoprenoid with Novel Enantiomer-selective Anti-influenza A Virus Activity Involving Nrf2 Activation.Control of Pim2 kinase stability and expression in transformed human haematopoietic cellsp63 the guardian of human reproduction.The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells.Curcumin inhibits HIV-1 by promoting Tat protein degradation.Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression.Proteasome regulates turnover of toxic human amylin in pancreatic cells.Dual function of MDM2 and MDMX toward the tumor suppressors p53 and RB.Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53.Basic mechanisms of neurodegeneration: a critical update.Context-dependent resistance to proteolysis of intrinsically disordered proteins.Intrinsically unstructured proteins and neurodegenerative diseases: conformational promiscuity at its best.NRF2 and p53: Januses in cancer?Two Degradation Pathways of the p35 Cdk5 (Cyclin-dependent Kinase) Activation Subunit, Dependent and Independent of UbiquitinationExpression of neddylation-related proteins in melanoma cell lines and the effect of neddylation on melanoma proliferation.Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types.The Atypical Ubiquitin E2 Conjugase UBE2L3 Is an Indirect Caspase-1 Target and Controls IL-1β Secretion by Inflammasomes.Proteasome-independent p53 degradation.High nuclear expression of proteasome activator complex subunit 1 predicts poor survival in soft tissue leiomyosarcomas.A metal carbonyl-protein needle composite designed for intracellular CO delivery to modulate NF-κB activity.E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ubiquitin-independent p53 proteasomal degradation.
@en
Ubiquitin-independent p53 proteasomal degradation.
@nl
type
label
Ubiquitin-independent p53 proteasomal degradation.
@en
Ubiquitin-independent p53 proteasomal degradation.
@nl
prefLabel
Ubiquitin-independent p53 proteasomal degradation.
@en
Ubiquitin-independent p53 proteasomal degradation.
@nl
P2860
P356
P1476
Ubiquitin-independent p53 proteasomal degradation
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2009.67
P577
2010-01-01T00:00:00Z