Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.
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MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent mannerIdentification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.A biomarker that identifies senescent human cells in culture and in aging skin in vivoChromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblastsStudies of Tumor Suppressor Genes via Chromosome EngineeringMapping a novel cellular-senescence gene to human chromosome 2q37 by irradiation microcell-mediated chromosome transfer.Identification and genetic mapping of a homeobox gene to the 4p16.1 region of human chromosome 4Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability.Replicative senescence of mesenchymal stem cells: a continuous and organized processA reassessment of the telomere hypothesis of senescence.The molecular genetics of cervical carcinoma.Molecular mechanism of carcinogenesis by human papillomavirus-16.Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA.Novel strategies for immortalization of human hepatocytes.Differential gene expression in SV40-mediated immortalization of human fibroblasts.Genetic and physical mapping on chromosome 4 narrows the localization of the gene for facioscapulohumeral muscular dystrophy (FSHD)The cultured diploid fibroblast as a model for the study of cellular aging.Cellular senescence.Senescence of immortal human fibroblasts by the introduction of normal human chromosome 6Human replicative senescence. A molecular studyA single locus on human chromosome 21 directs the expression of a receptor for adenovirus type 2 in mouse A9 cells.Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortalityWild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.A gene involved in control of human cellular senescence on human chromosome 1qAltered chromosome 6 in immortal human fibroblastsAre there tumor suppressor genes on chromosome 4p in sporadic colorectal carcinoma?Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: subregional mapping of chromosome 4 in cervical carcinoma.A mortality gene(s) for the human adenocarcinoma line HeLa maps to a 130-kb region of human chromosome 4q22-q23Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4.Extended lifespan and immortalization of human fibroblasts induced by X-ray irradiation.An integrated genomic, transcriptional and protein investigation of FGFRL1 as a putative 4p16.3 deletion target in bladder cancer.Evidence for a genetic basis for the model system of cellular senescence.Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions.Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.Chromosomal influence on hybrid cell proliferation.Establishment of spontaneously immortalized rat type 1 astroglial cell lines: the role of p53 in astroglial carcinogenesis.Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7.
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Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genetic analysis of indefinite ...... a cell senescence-related gene
@nl
Genetic analysis of indefinite ...... gene(s) on human chromosome 4.
@en
type
label
Genetic analysis of indefinite ...... a cell senescence-related gene
@nl
Genetic analysis of indefinite ...... gene(s) on human chromosome 4.
@en
prefLabel
Genetic analysis of indefinite ...... a cell senescence-related gene
@nl
Genetic analysis of indefinite ...... gene(s) on human chromosome 4.
@en
P2093
P2860
P356
P1476
Genetic analysis of indefinite ...... gene(s) on human chromosome 4.
@en
P2093
A M Killary
D H Ledbetter
O M Pereira-Smith
P2860
P304
P356
10.1073/PNAS.88.13.5635
P407
P577
1991-07-01T00:00:00Z