Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain - Wikidata - wikimedia - TriplyDB

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

http://www.wikidata.org/entity/Q37543496

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Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke TGFbeta1 stimulates the over-production of white matter astrocytes from precursors of the "brain marrow" in a rodent model of neonatal encephalopathy Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?The central role of hypothalamic inflammation in the acute illness response and cachexia Peptides at the blood brain barrier: Knowing me knowing you Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cepsilon-dependent manner.Stromal regulation of vessel stability by MMP14 and TGFbeta.Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?CD8 T cell-initiated vascular endothelial growth factor expression promotes central nervous system vascular permeability under neuroinflammatory conditions.Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences Claudins and the modulation of tight junction permeability.Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier Targeting the neurovascular unit for treatment of neurological disorders.TGFβs modulate permeability of the blood-epididymis barrier in an in vitro model Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery.Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery.Transforming growth factor-β1 regulates Cdk5 activity in primary sensory neurons.Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model.STAT3-mediated astrogliosis protects myelin development in neonatal brain injury.Brain endothelial dysfunction in cerebral adrenoleukodystrophy.Targeted drug delivery to treat pain and cerebral hypoxia Tight junction modulation of the blood brain barrier: CNS delivery of small molecules Neurovascular unit in chronic pain.Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery.Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism TGFβ1 exacerbates blood-brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5 Altered expression of claudin family proteins in Alzheimer's disease and vascular dementia brains.Tight junction proteins expression and modulation in immune cells and multiple sclerosis Heterogeneity of microglial activation in the innate immune response in the brain.Cytokine signaling modulates blood-brain barrier function.Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery.Transforming growth factor-β in normal nociceptive processing and pathological pain models.Breaking the barrier in stroke: what should we know? A mini-review.Regulation of claudins in blood-tissue barriers under physiological and pathological states P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery.Drug delivery to the ischemic brain.

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Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

http://www.wikidata.org/entity/Q37543496

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 25 March 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Transforming growth factor-bet ...... rrier during inflammatory pain

@en

Transforming growth factor-bet ...... rier during inflammatory pain.

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type

label

Transforming growth factor-bet ...... rrier during inflammatory pain

@en

Transforming growth factor-bet ...... rier during inflammatory pain.

@nl

prefLabel

Transforming growth factor-bet ...... rrier during inflammatory pain

@en

Transforming growth factor-bet ...... rier during inflammatory pain.

@nl

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Journal of Cerebral Blood Flow & Metabolism

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Transforming growth factor-bet ...... rrier during inflammatory pain

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Christine M Solinsky

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Kristin M Demarco

http://www.w3.org/2001/XMLSchema#string

Lucy Sanchez-Covarrubias

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Patrick T Ronaldson

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Thomas P Davis

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P2860

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin

Role of claudin interactions in airway tight junctional permeability

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

Protein kinase C regulates the phosphorylation and cellular localization of occludin

Claudin 5 is transiently expressed during the development of the retinal pigment epithelium

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1084-1098

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scholarly article

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10.1038/JCBFM.2009.32

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6

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29

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2009-03-25T00:00:00Z

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24232086

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19319146

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blood–brain barrier

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3910515

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