The epothilones: how pharmacology relates to clinical utility. - Wikidata - wikimedia - TriplyDB

The epothilones: how pharmacology relates to clinical utility.

The epothilones: how pharmacology relates to clinical utility.

http://www.wikidata.org/entity/Q37543912

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Using chemobiosynthesis and synthetic mini-polyketide synthases to produce pharmaceutical intermediates in Escherichia coli.Optimizing ixabepilone treatment schedules in patients with advanced or metastatic breast cancer.Differential in vitro sensitivity to patupilone versus paclitaxel in uterine and ovarian carcinosarcoma cell lines is linked to tubulin-beta-III expression Adjuvant therapy of triple negative breast cancer.New microtubule-inhibiting anticancer agents.Epothilones in the treatment of ovarian cancer.Successful rechallenge after ixabepilone-induced radiation recall dermatitis using an alternative dosing strategy.Molecular modeling study on the tubulin-binding modes of epothilone derivatives: Insight into the structural basis for epothilones activity.The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.

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The epothilones: how pharmacology relates to clinical utility.

http://www.wikidata.org/entity/Q37543912

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The epothilones: how pharmacology relates to clinical utility.

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The epothilones: how pharmacology relates to clinical utility.

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The epothilones: how pharmacology relates to clinical utility.

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The epothilones: how pharmacology relates to clinical utility.

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The epothilones: how pharmacology relates to clinical utility.

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The epothilones: how pharmacology relates to clinical utility.

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Annals of Pharmacotherapy

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The epothilones: how pharmacology relates to clinical utility.

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Laura Boehnke Michaud

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Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment

Epothilones: mechanism of action and biologic activity

Pharmacokinetics and pharmacodynamics of estramustine phosphate

Phase I study of the novel epothilone analog ixabepilone (BMS-247550) in patients with advanced solid tumors and lymphomas

THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS

Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: a Southwest Oncology Group trial S0111.

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group.

Paclitaxel in cancer therapy.

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells.

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1294-1309

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scholarly article

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10.1345/APH.1M005

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2009-07-07T00:00:00Z

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26653876

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19584389

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