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Induction of tumor cell death through targeting tubulin and evoking dysregulation of cell cycle regulatory proteins by multifunctional cinnamaldehydesSynthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.Drugs that target dynamic microtubules: a new molecular perspectiveNovel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity.Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agentsConcise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.Kinesin 18A expression: clinical relevance to colorectal cancer progression.WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects.Combined Molecular Docking, 3D-QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine-binding Site.Synthesis and biological evaluation of simplified pironetin analogues with modifications in the side chain and the lactone ring.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
New microtubule-inhibiting anticancer agents.
@en
New microtubule-inhibiting anticancer agents.
@nl
type
label
New microtubule-inhibiting anticancer agents.
@en
New microtubule-inhibiting anticancer agents.
@nl
prefLabel
New microtubule-inhibiting anticancer agents.
@en
New microtubule-inhibiting anticancer agents.
@nl
P2093
P2860
P1476
New microtubule-inhibiting anticancer agents.
@en
P2093
Ling-Hua Meng
Si-Meng Chen
P2860
P304
P356
10.1517/13543780903571631
P407
P577
2010-03-01T00:00:00Z