Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
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Dystrophin-deficient large animal models: translational research and exon skippingNanoparticle delivery of antisense oligonucleotides and their application in the exon skipping strategy for Duchenne muscular dystrophyDifferential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell TransplantationDystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures.A comparative study of N-glycolylneuraminic acid (Neu5Gc) and cytotoxic T cell (CT) carbohydrate expression in normal and dystrophin-deficient dog and human skeletal muscleAnimal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapyRecent advances using zebrafish animal models for muscle disease drug discoveryA computerized MRI biomarker quantification scheme for a canine model of Duchenne muscular dystrophyChemical shift-based MRI to measure fat fractions in dystrophic skeletal muscle.Characteristics of magnetic resonance imaging biomarkers in a natural history study of golden retriever muscular dystrophySkeletal Muscle Quantitative Nuclear Magnetic Resonance Imaging and Spectroscopy as an Outcome Measure for Clinical TrialsGait characterization in golden retriever muscular dystrophy dogs using linear discriminant analysis.Application of fluorescence two-dimensional difference in-gel electrophoresis as a proteomic biomarker discovery tool in muscular dystrophy researchThe golden retriever model of Duchenne muscular dystrophy.Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients.Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trialsAsynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.The role of proteases in excitation-contraction coupling failure in muscular dystrophy.Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.Clinical phenotype of X-linked myotubular myopathy in Labrador Retriever puppies.Motor physical therapy affects muscle collagen type I and decreases gait speed in dystrophin-deficient dogs.NBD delivery improves the disease phenotype of the golden retriever model of Duchenne muscular dystrophy.Duchenne muscular dystrophy gene therapy in the canine model.Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies.Identification in GRMD dog muscle of critical miRNAs involved in pathophysiology and effects associated with MuStem cell transplantation.Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophyMRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy.Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography.GRMD cardiac and skeletal muscle metabolism gene profiles are distinctAbsence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy.The pharmacology of regenerative medicineLevels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy.Comparative Genomics of X-linked Muscular Dystrophies: The Golden Retriever ModelTadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory macrophages.Respiratory dysfunction in unsedated dogs with golden retriever muscular dystrophy.Dystrophin insufficiency causes selective muscle histopathology and loss of dystrophin-glycoprotein complex assembly in pig skeletal muscle.Diaphragm remodeling and compensatory respiratory mechanics in a canine model of Duchenne muscular dystrophy.Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin α2 surrogates.
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Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 05 January 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@en
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@nl
type
label
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@en
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@nl
prefLabel
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@en
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@nl
P2093
P2860
P50
P1433
P1476
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
@en
P2093
Bruce P Keene
C Aaron Larsen
Daniel J Bogan
David A Detwiler
Eric P Hoffman
Janet R Bogan
Jiahui Wang
Joe N Kornegay
Peter Nghiem
P2860
P2888
P304
P356
10.1007/S00335-011-9382-Y
P577
2012-01-05T00:00:00Z