Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.
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Candidate genes for COPD: current evidence and researchEarly events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cellsHIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype.Integrative genomics of chronic obstructive pulmonary disease.Airway basal cells. The "smoking gun" of chronic obstructive pulmonary diseaseEndothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells.Smoking-Associated Disordering of the Airway Basal Stem/Progenitor Cell Metabotype.Increased expression of TROP2 in airway basal cells potentially contributes to airway remodeling in chronic obstructive pulmonary disease.Association of chromosome 19 to lung cancer genotypes and phenotypes.Chronic Obstructive Pulmonary Disease Genetics: A Review of the Past and a Look Into the FutureWNT Signaling in Lung Aging and Disease.POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers.β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction.Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung.Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis.Is Chronic Obstructive Pulmonary Disease an Accelerated Aging Disease?Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium.Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes.COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production.The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates.Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration.Detection of a 4-bp Insertion/deletion Polymorphism within the Promoter of EGLN2 Using Mismatch PCR-RFLP and Its Association with Susceptibility to Breast Cancer
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Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
@en
Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
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Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
@en
Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
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Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
@en
Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
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Smoking dysregulates the human ...... me at COPD risk locus 19q13.2.
@en
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Dorothy M Ryan
Francisco Agosto-Perez
Jacqueline Salit
Jason G Mezey
Lauren J Buro-Auriemma
Matthew S Walters
Neil R Hackett
Renat Shaykhiev
Robert J Downey
Ronald G Crystal
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P304
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10.1371/JOURNAL.PONE.0088051
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2014-02-03T00:00:00Z