PAK4 kinase is essential for embryonic viability and for proper neuronal development - Wikidata - wikimedia - TriplyDB

PAK4 kinase is essential for embryonic viability and for proper neuronal development

PAK4 kinase is essential for embryonic viability and for proper neuronal development

http://www.wikidata.org/entity/Q28205608

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The emerging importance of group II PAKs Huntingtin promotes cell survival by preventing Pak2 cleavage GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo Small G proteins in the cardiovascular system: physiological and pathological aspects PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1 Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?Signaling, Regulation, and Specificity of the Type II p21-activated Kinases Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion.Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice PAK signalling during the development and progression of cancer Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice The serine-threonine protein kinase PAK4 is dispensable in zebrafish: identification of a morpholino-generated pseudophenotype p21-Activated Kinase 4 Promotes Intimal Hyperplasia and Vascular Smooth Muscle Cells Proliferation during Superficial Femoral Artery Restenosis after Angioplasty.Maternal pak4 expression is required for primitive myelopoiesis in zebrafish Integrin-mediated cell attachment induces a PAK4-dependent feedback loop regulating cell adhesion through modified integrin alpha v beta 5 clustering and turnover.Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.Differential sensitivity of Pak5, Pak6, and Pak5/Pak6 double-knockout mice to the stimulant effects of amphetamine and exercise-induced alterations in body weight.Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.Republished: tracing PAKs from GI inflammation to cancer PAK1 as a therapeutic target.Essential role for the SLK protein kinase in embryogenesis and placental tissue development.A proteomic approach for the identification of novel lysine methyltransferase substrates.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish.Nucleostemin maintains self-renewal of embryonic stem cells and promotes reprogramming of somatic cells to pluripotency.Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma Targeted disruption of the gene for the PAK5 kinase in mice.A tale of two Paks.SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart.Pak protein kinases and their role in cancer.PAK signaling in oncogenesis.Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.Increased Circulating Endothelial Microparticles Associated with PAK4 Play a Key Role in Ventilation-Induced Lung Injury Process

P2860

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P2860

PAK4 kinase is essential for embryonic viability and for proper neuronal development

http://www.wikidata.org/entity/Q28205608

description

2003 nî lūn-bûn

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2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

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2003年論文

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2003年论文

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name

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@ast

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@en

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@nl

type

label

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@ast

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@en

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@nl

prefLabel

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@ast

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@en

PAK4 kinase is essential for embryonic viability and for proper neuronal development

@nl

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MCB.23.20.7122-7133.2003

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Molecular and Cellular Biology

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PAK4 kinase is essential for embryonic viability and for proper neuronal development

@en

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Amer A Beg

http://www.w3.org/2001/XMLSchema#string

Audrey Minden

http://www.w3.org/2001/XMLSchema#string

Bennet G Novitch

http://www.w3.org/2001/XMLSchema#string

Jian Qu

http://www.w3.org/2001/XMLSchema#string

Jian-Ming Xie

http://www.w3.org/2001/XMLSchema#string

Matthew Kohn

http://www.w3.org/2001/XMLSchema#string

Roderick Bronson

http://www.w3.org/2001/XMLSchema#string

Spencer Kozinn

http://www.w3.org/2001/XMLSchema#string

Xiaofan Li

http://www.w3.org/2001/XMLSchema#string

Ye Zheng

http://www.w3.org/2001/XMLSchema#string

P2860

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration

Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

PAK4 is activated via PI3K in HGF-stimulated epithelial cells

Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6

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7122-33

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10.1128/MCB.23.20.7122-7133.2003

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14517283

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