The spliceosome: a self-organized macromolecular machine in the nucleus?
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The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicingThe nuts and bolts of the endogenous spliceosomeThe Prp19 complex directly functions in mitotic spindle assemblyOrganization of Plasmodium falciparum spliceosomal core complex and role of arginine methylation in its assemblyDiscovery of a splicing regulator required for cell cycle progressionPhosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.The N-terminus of Prp1 (Prp6/U5-102 K) is essential for spliceosome activation in vivo.Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity.Modelling reveals kinetic advantages of co-transcriptional splicingSupraspliceosomes at defined functional states portray the pre-assembled nature of the pre-mRNA processing machine in the cell nucleus.The perichromatin region of the plant cell nucleus is the area with the strongest co-localisation of snRNA and SR proteins.The Ssu72 phosphatase mediates the RNA polymerase II initiation-elongation transition.An SF1 affinity model to identify branch point sequences in human introns.Transcriptomic characterization of cold acclimation in larval zebrafishLimiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing.The timing of pre-mRNA splicing visualized in real-timeLoss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.Hypoxia elicits broad and systematic changes in protein subcellular localization.Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant.Son maintains accurate splicing for a subset of human pre-mRNAs.Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome ActivationCo-transcriptional regulation of alternative pre-mRNA splicingGenome-wide activation of latent donor splice sites in stress and disease.An evolutionarily conserved innate immunity protein interaction network.The function of spliceosome components in open mitosis.How a neutral evolutionary ratchet can build cellular complexity.Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells.Probing nucleic acid interactions and pre-mRNA splicing by Förster Resonance Energy Transfer (FRET) microscopyPhosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone MethylationEvidence of function for conserved noncoding sequences in Arabidopsis thaliana.A mechanism for a single nucleotide intron shift.Mechanobiology of Chromatin and the Nuclear Interior.The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.Changes in intranuclear mobility of mature snRNPs provide a mechanism for splicing defects in spinal muscular atrophy.The global cancer genomics consortium's third annual symposium: from oncogenomics to cancer care.Co-transcriptional splicing and the CTD code.Diversification of the muscle proteome through alternative splicing.RNA seeds nuclear bodies
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P2860
The spliceosome: a self-organized macromolecular machine in the nucleus?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 17 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The spliceosome: a self-organized macromolecular machine in the nucleus?
@en
The spliceosome: a self-organized macromolecular machine in the nucleus?
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type
label
The spliceosome: a self-organized macromolecular machine in the nucleus?
@en
The spliceosome: a self-organized macromolecular machine in the nucleus?
@nl
prefLabel
The spliceosome: a self-organized macromolecular machine in the nucleus?
@en
The spliceosome: a self-organized macromolecular machine in the nucleus?
@nl
P1476
The spliceosome: a self-organized macromolecular machine in the nucleus?
@en
P304
P356
10.1016/J.TCB.2009.05.004
P577
2009-07-17T00:00:00Z