Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
about
Iron dysregulation in Huntington's diseaseAutophagy and neurodegenerationAutophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's diseaseTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesReinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.Striatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Rhes suppression enhances disease phenotypes in Huntington's disease micePreclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiologyBeclin 1 biology and its role in heart disease.Sea lampreys elicit strong transcriptomic responses in the lake trout liver during parasitismThe altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosisImpaired TrkB Signaling Underlies Reduced BDNF-Mediated Trophic Support of Striatal Neurons in the R6/2 Mouse Model of Huntington's Disease.A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells.RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.Ubiquitin pathways in neurodegenerative disease.Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.mTOR in Brain Physiology and Pathologies.Decreased Rhes mRNA levels in the brain of patients with Parkinson's disease and MPTP-treated macaques.Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts.Autophagy-from molecular mechanisms to clinical relevance.The Small GTP-Binding Protein Rhes Influences Nigrostriatal-Dependent Motor Behavior During Aging.Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age.Association Between Autophagy and Neurodegenerative Diseases.
P2860
Q26829932-662CFD52-073F-496C-83AC-818E3798D65DQ26991692-FF569306-963B-423D-A092-071F653CC1C7Q27011387-F82FC2E2-F395-4901-94B7-175FA5940368Q27011417-386EA281-5B2F-45F4-AEBD-6791D3A99BA1Q27021382-95C94164-A042-4903-8D4C-F9DFDAAB8955Q27306293-23ECF4E2-C98C-4E26-BC34-F7096961D5A8Q33831774-BDF55E3A-3F9C-43CC-8F8E-BD1C003FB152Q34071922-EECBD3BE-39C1-43FC-98BC-AC91AC874498Q34284039-E19965BF-AC7C-4D66-8E89-D53711686342Q36011788-25D68559-42DA-48BD-A961-645B2BB67903Q36021771-4CA1474F-A974-4C95-A20E-79E885BAA0D6Q36112209-2908320A-70BE-48D7-B999-2D395D1915E4Q36225846-8A0599D0-D114-4D9D-B8B6-3AE0471627ADQ36665616-29F9224F-5EE3-4C02-B590-7363CE4A1C0EQ37265679-22708CA4-2A79-400E-99B0-08557BFDAB3AQ37482165-3D6A76F7-E154-4096-8197-B4DF4989C7AFQ38234883-D158EE5C-3FAB-4B5A-AC1E-AE97749EED23Q38447132-280D3E89-94C2-41AC-9FF8-9401B592EA73Q38565769-BBE05B74-D509-4E6D-B288-63FDA1C29309Q38662191-6503C8F8-2B02-4E6B-83A9-4C4E5A93F8E5Q38792714-86FC7653-D9AB-4D19-8E53-1C33D55D5B76Q39037205-ECEAC847-B3E8-4F7B-A466-F11442AA7158Q48923348-452A5F96-86AD-4BBB-A923-F8BA6A01F3E6Q52605399-E8B57BF0-7449-4264-909E-099714D6E81CQ55119787-A72898B5-22E8-4B8D-AA2D-18D797F11252Q55315355-1D783803-4C70-4C22-BF7B-D64FB9B53BF9
P2860
Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@en
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@nl
type
label
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@en
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@nl
prefLabel
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@en
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@nl
P2093
P2860
P921
P356
P1476
Rhes, a striatal-selective pro ...... lin-1 and activates autophagy.
@en
P2093
Alexandra J Murray
Neelam Shahani
Robert G Mealer
Srinivasa Subramaniam
P2860
P304
P356
10.1074/JBC.M113.536912
P407
P577
2013-12-09T00:00:00Z