Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.
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Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulatorHuman cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexesAdapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayStress Beyond Translation: Poxviruses and MoremTOR Regulation of Lymphoid Cells in Immunity to PathogensImmunosuppressive potency of mechanistic target of rapamycin inhibitors in solid-organ transplantationHuman Cytomegalovirus Strategies to Maintain and Promote mRNA TranslationActivation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral ReplicationViruses and autophagyHow I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipientsInterference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma HerpesvirusesAn invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathwayRegulation of the mTOR complex 1 pathway by nutrients, growth factors, and stressAntiviral drug resistance of human cytomegalovirus.Regulation of host translational machinery by African swine fever virus.Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.Effects of simian virus 40 large and small tumor antigens on mammalian target of rapamycin signaling: small tumor antigen mediates hypophosphorylation of eIF4E-binding protein 1 late in infection.Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication.Regulation of the translation initiation factor eIF4F by multiple mechanisms in human cytomegalovirus-infected cells.Metabolomics in drug target discovery.mTOR signaling for biological control and cancer.Assembly of an active translation initiation factor complex by a viral protein.Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replicationTranslational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cellsNoncytotoxic inhibition of viral infection through eIF4F-independent suppression of translation by 4EGi-1Human cytomegalovirus activates glucose transporter 4 expression to increase glucose uptake during infectionPKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.Frontier of epilepsy research - mTOR signaling pathway.Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.The human cytomegalovirus protein pUL38 suppresses endoplasmic reticulum stress-mediated cell death independently of its ability to induce mTORC1 activation.Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switchAMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection.The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38.Poly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells.Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysisDynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells.
P2860
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P2860
Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@en
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@nl
type
label
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@en
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@nl
prefLabel
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@en
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@nl
P2093
P2860
P1433
P1476
Human cytomegalovirus infectio ...... ream effectors of mTOR kinase.
@en
P2093
James C Alwine
Sagar B Kudchodkar
Tobi G Maguire
Yongjun Yu
P2860
P304
11030-11039
P356
10.1128/JVI.78.20.11030-11039.2004
P407
P577
2004-10-01T00:00:00Z