Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor.
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ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Insulin receptor antibody-sulfamidase fusion protein penetrates the primate blood-brain barrier and reduces glycosoaminoglycans in Sanfilippo type A cells.Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transportOvercoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.Effective treatment of glioblastoma requires crossing the blood-brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicineConcomitant Use of Neuroprotective Drugs in Neuro Rehabilitation of Multiple Sclerosis.Gene therapy for the neurological manifestations in lysosomal storage disorders.Immunotherapy for Alzheimer's disease: past, present and futureTargeted delivery of protein and gene medicines through the blood-brain barrier.Recent advances in gene therapy for lysosomal storage disorders.Challenges and new strategies for therapeutic peptide delivery to the CNS.Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives.Delivery of Biologics Across the Blood-Brain Barrier with Molecular Trojan Horse Technology.Enzymes as Immunotherapeutics.Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation
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Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 25 December 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
Pharmacokinetics and brain upt ...... st the human insulin receptor.
@en
Pharmacokinetics and brain upt ...... st the human insulin receptor.
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type
label
Pharmacokinetics and brain upt ...... st the human insulin receptor.
@en
Pharmacokinetics and brain upt ...... st the human insulin receptor.
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prefLabel
Pharmacokinetics and brain upt ...... st the human insulin receptor.
@en
Pharmacokinetics and brain upt ...... st the human insulin receptor.
@nl
P2093
P2860
P356
P1476
Pharmacokinetics and brain upt ...... st the human insulin receptor.
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P2093
Eric K-W Hui
Jeff Zhiqiang Lu
Rachita K Sumbria
P2860
P304
P356
10.1002/BIT.24795
P577
2012-12-25T00:00:00Z