When mutants gain new powers: news from the mutant p53 field.
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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathwayMutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasionBarrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesisThe first 30 years of p53: growing ever more complexOncogenic Intra-p53 Family Member Interactions in Human CancersMutant p53: One, No One, and One Hundred ThousandMutant p53: Multiple Mechanisms Define Biologic Activity in CancerNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2The Role of TP53 Gene Codon 72 Polymorphism in Leukemia: A PRISMA-Compliant Systematic Review and Meta-AnalysisThe complexity of epigenetic diseasesIs cancer a metabolic disease?Links between mutant p53 and genomic instabilityModeling AEC-New approaches to study rare genetic disordersTumor suppressor p53 and its gain-of-function mutants in cancerResistance and gain-of-resistance phenotypes in cancers harboring wild-type p53Targeting DNA damage response in cancer therapyBiophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticlesDisruptive chemicals, senescence and immortalityG-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53.p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressThe rebel angel: mutant p53 as the driving oncogene in breast cancer.The p53 pathway as a target in cancer therapeutics: obstacles and promiseGain of function of mutant p53: R282W on the peak?Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage responseConnecting molecular pathways to hereditary cancer risk syndromesDegradation of p53 by human Alphapapillomavirus E6 proteins shows a stronger correlation with phylogeny than oncogenicityHigh-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888Functional DNA repair signature of cancer cell lines exposed to a set of cytotoxic anticancer drugs using a multiplexed enzymatic repair assay on biochipThe C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivoTriptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradationArsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligaseGain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug SensitivitySPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63p73 as a pharmaceutical target for cancer therapyMutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.The p53-microRNA-34a axis regulates cellular entry receptors for tumor-associated human herpes viruses.A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapyMolecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma.Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.
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When mutants gain new powers: news from the mutant p53 field.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
When mutants gain new powers: news from the mutant p53 field.
@en
When mutants gain new powers: news from the mutant p53 field.
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type
label
When mutants gain new powers: news from the mutant p53 field.
@en
When mutants gain new powers: news from the mutant p53 field.
@nl
prefLabel
When mutants gain new powers: news from the mutant p53 field.
@en
When mutants gain new powers: news from the mutant p53 field.
@nl
P356
P1476
When mutants gain new powers: news from the mutant p53 field
@en
P2093
Varda Rotter
P2888
P304
P356
10.1038/NRC2693
P407
P50
P577
2009-08-20T00:00:00Z