Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.
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The B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transductionIdentification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signalingAssociation of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophilsIsoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk geneLeupaxin negatively regulates B cell receptor signalingBcr-Abl oncoproteins bind directly to activators of the Ras signalling pathwayThe direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathwaysInterleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell lineHuman spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoproteinActivation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signalingBinding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interactionTyrosine phosphorylation of CD19 in pre-B and mature B cellsDual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorMapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kAssociation between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinasesAn Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinasesA double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signalsInhibition of the B cell by CD22: a requirement for LynIn vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylationRegulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitinationHematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cellsRole of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signalingIdentification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signalingPhysical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and LynSignal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2Signal transduction by immunoglobulin is mediated through Ig alpha and Ig betaActivation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoterPaired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1Tyrosine phosphorylation of the vav proto-oncogene product in activated B cellsAssociation of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteinsThe membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell lineAssociation of Src-like protein tyrosine kinases with the CD2 cell surface molecule in rat T lymphocytes and natural killer cellsAltered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient miceImpaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient miceSyk activation by the Src-family tyrosine kinase in the B cell receptor signalingp120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinasePredominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytesTemporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
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P2860
Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@en
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@nl
type
label
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@en
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@nl
prefLabel
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@en
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@nl
P2093
P2860
P356
P1476
Anti-immunoglobulin stimulatio ...... ated protein-tyrosine kinases.
@en
P2093
A L Burkhardt
M Brunswick
P2860
P304
P356
10.1073/PNAS.88.16.7410
P407
P577
1991-08-01T00:00:00Z